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Literature summary for 3.2.2.4 extracted from

  • Parkin, D.W.; Schramm, V.L.
    Effects of allosteric activation on the primary and secondary kinetic isotope effects for three AMP nucleosidases (1984), J. Biol. Chem., 259, 9418-9425.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
MgATP2-
-
Escherichia coli
MgATP2-
-
Azotobacter vinelandii

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
15
-
AMP
-
Escherichia coli
15
-
AMP
-
Azotobacter vinelandii

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
AMP + H2O Escherichia coli
-
?
-
?
AMP + H2O Azotobacter vinelandii
-
?
-
?

Organism

Organism UniProt Comment Textmining
Azotobacter vinelandii
-
-
-
Escherichia coli
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Escherichia coli
-
Azotobacter vinelandii

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
24
-
-
Escherichia coli
34
-
-
Azotobacter vinelandii

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-aminoAMP + H2O
-
Azotobacter vinelandii 2-aminoadenine + D-ribose 5-phosphate
-
?
3'-deoxy-5'-AMP
-
Azotobacter vinelandii ?
-
?
8-azaAMP
-
Azotobacter vinelandii 8-azaadenine + D-ribose 5-phosphate
-
?
AMP + H2O
-
Escherichia coli adenine + ribose 5-phosphate
-
?
AMP + H2O
-
Azotobacter vinelandii adenine + ribose 5-phosphate
-
?
AMP + H2O
-
Escherichia coli ?
-
?
AMP + H2O
-
Azotobacter vinelandii ?
-
?