Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli as a His-tagged protein | Campylobacter jejuni |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.001 | - |
6-amino-6-deoxyfutalosine | pH 7, 25°C | Campylobacter jejuni |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
6-amino-6-deoxyfutalosine + H2O | Campylobacter jejuni | the enzyme is part of a modified futalosine pathway for menaquinone biosynthesis | dehypoxanthine futalosine + adenine | - |
? | |
6-amino-6-deoxyfutalosine + H2O | Campylobacter jejuni NCTC 11168 | the enzyme is part of a modified futalosine pathway for menaquinone biosynthesis | dehypoxanthine futalosine + adenine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Campylobacter jejuni | Q0PC20 | - |
- |
Campylobacter jejuni NCTC 11168 | Q0PC20 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Campylobacter jejuni |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
6-amino-6-deoxyfutalosine + H2O | the enzyme is part of a modified futalosine pathway for menaquinone biosynthesis | Campylobacter jejuni | dehypoxanthine futalosine + adenine | - |
? | |
6-amino-6-deoxyfutalosine + H2O | 6-amino-6-deoxyfutalosine i.e. 3-[3-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]propanoyl]benzoate. The activity with futalosine ist 2% compared to the activity with 6-amino-6-deoxyfutalosine. The enzyme also has the activity of EC 3.2.2.9, adenosylhomocysteine nucleosidase | Campylobacter jejuni | dehypoxanthine futalosine + adenine | dehypoxanthine futalosine i.e. 3-[3-[(2R,3S,4R)-3,4,5-trihydroxytetrahydrofuran-2-yl]propanoyl]benzoate | ? | |
6-amino-6-deoxyfutalosine + H2O | the enzyme is part of a modified futalosine pathway for menaquinone biosynthesis | Campylobacter jejuni NCTC 11168 | dehypoxanthine futalosine + adenine | - |
? | |
6-amino-6-deoxyfutalosine + H2O | 6-amino-6-deoxyfutalosine i.e. 3-[3-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]propanoyl]benzoate. The activity with futalosine ist 2% compared to the activity with 6-amino-6-deoxyfutalosine. The enzyme also has the activity of EC 3.2.2.9, adenosylhomocysteine nucleosidase | Campylobacter jejuni NCTC 11168 | dehypoxanthine futalosine + adenine | dehypoxanthine futalosine i.e. 3-[3-[(2R,3S,4R)-3,4,5-trihydroxytetrahydrofuran-2-yl]propanoyl]benzoate | ? |
Synonyms | Comment | Organism |
---|---|---|
AFL nucleosidase | - |
Campylobacter jejuni |
aminofutalosine nucleosidase | - |
Campylobacter jejuni |
Cj0117 | - |
Campylobacter jejuni |
methylthioadenosine nucleosidase | - |
Campylobacter jejuni |
MqnB | - |
Campylobacter jejuni |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
25 | - |
assay at | Campylobacter jejuni |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.53 | - |
6-amino-6-deoxyfutalosine | pH 7, 25°C | Campylobacter jejuni |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | - |
assay at | Campylobacter jejuni |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme is part of a modified futalosine pathway for menaquinone biosynthesis | Campylobacter jejuni |