Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | before germinal vesicle breakdown the enzyme is released from the nucleus into the cytoplasm | Mus musculus | 5737 | - |
nucleus | - |
Mus musculus | 5634 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
thymine-mismatched double-stranded DNA + H2O | Mus musculus | - |
thymine + double-stranded DNA with abasic site | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
oocyte | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
thymine-mismatched double-stranded DNA + H2O | - |
Mus musculus | thymine + double-stranded DNA with abasic site | - |
? |
Synonyms | Comment | Organism |
---|---|---|
TDG | - |
Mus musculus |
thymine DNA glycosylase | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme functions in base excision repair and also acts as a key enzyme that participates in active DNA demethylation. Aberrant enzyme expression causes epigenetic modifications and meiotic cell cycle arrest of mouse oocytes | Mus musculus |