Literature summary for 3.2.2.23 extracted from

Arantes, L.S.; Nova, L.G.; Resende, B.C.; Bitar, M.; Coelho, I.E.; Miyoshi, A.; Azevedo, V.A.; Lara Dos Santos, L.; Machado, C.R.; de Oliveira Lopes, D.
The Corynebacterium pseudotuberculosis genome contains two formamidopyrimidine-DNA glycosylase enzymes, only one of which recognizes and excises 8-oxoguanine lesion (2016), Gene, 575, 233-243 .

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Cloned(Commentary)

Cloned (Comment)	Organism
expression in Escherichia coli	Corynebacterium pseudotuberculosis

Crystallization (Commentary)

Crystallization (Comment)	Organism
homology modeling of structure	Corynebacterium pseudotuberculosis

Organism

Organism	UniProt	Comment	Textmining
Corynebacterium pseudotuberculosis	D9QB78	-	-
Corynebacterium pseudotuberculosis 231	D9QB78	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
60mer containing 8-oxoguanine + H2O	-	Corynebacterium pseudotuberculosis	60mer with an abasic site + 8-oxoguanine	-	?
60mer containing 8-oxoguanine + H2O	-	Corynebacterium pseudotuberculosis 231	60mer with an abasic site + 8-oxoguanine	-	?

Subunits

Subunits	Comment	Organism
?	x * 36000, SDS-PAGE, recombinant His-tagged protein	Corynebacterium pseudotuberculosis

Synonyms

Synonyms	Comment	Organism
MutM1	-	Corynebacterium pseudotuberculosis

General Information

General Information	Comment	Organism
physiological function	overexpression of MutM1 or CpMutM2 has toxic effects on Escherichia coli strain BH20 which lacks MutM activity. Overexpression in Escheirchia coli leads to increased sensitivity to H2O2	Corynebacterium pseudotuberculosis

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Release 2023.1 (January 2023)