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Literature summary for 3.2.2.23 extracted from

  • Dusinska, M.; Dzupinkova, Z.; Wsolova, L.; Harrington, V.; Collins, A.R.
    Possible involvement of XPA in repair of oxidative DNA damage deduced from analysis of damage, repair and genotype in a human population study (2006), Mutagenesis, 21, 205-211.
    View publication on PubMed

Application

Application Comment Organism
medicine study on the polymorphism 23A to G in the DNA repair gene XPA. Presence of the A allele is associated with higher levels of DNA damage as well as with higher activity of the OGG1 8-oxoguanidine DNA glycosylase. In individuals with the A allele, OGG1 repair activity also increases with age Homo sapiens

Protein Variants

Protein Variants Comment Organism
additional information study on the polymorphism 23A to G in the DNA repair gene XPA. Presence of the A allele is associated with higher levels of DNA damage as well as with higher activity of the OGG1 8-oxoguanidine DNA glycosylase. In individuals with the A allele, OGG1 repair activity also increases with age Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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