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Literature summary for 3.2.2.22 extracted from
- Characterization of ricin toxin family members from Ricinus communis (2010), Toxicon, 55, 658-661.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression of RTA and each of the six RLPs in polyhistidine-tagged form in Escherichia coli BL21-AI cells | Ricinus communis |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Ricinus communis | ricin inhibits translation by removal of a specific adenine from 28S RNA, all seven full-length ricin family members are active | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Ricinus communis | - |
seven full-length ricin family member ricin-A-chain, RTA, and ricin-like proteins RLP1-6 | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| recombinant His-tagged RTA and RLPs from Escherichia coli BL21-AI cells by nickel affinity chromatography | Ricinus communis |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | ricin inhibits translation by removal of a specific adenine from 28S RNA, all seven full-length ricin family members are active | Ricinus communis | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ricin | - |
Ricinus communis |
| ricin-A-chain | - |
Ricinus communis |
| ricin-like protein | - |
Ricinus communis |
| RLP1 | - |
Ricinus communis |
| RLP2 | - |
Ricinus communis |
| RLP3 | - |
Ricinus communis |
| RLP4 | - |
Ricinus communis |
| RLP5 | - |
Ricinus communis |
| RLP6 | - |
Ricinus communis |
| RTA | - |
Ricinus communis |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 30 | - |
assay at | Ricinus communis |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 5.6 | - |
assay at | Ricinus communis |
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Release 2023.1 (January 2023)
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