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Literature summary for 3.2.2.22 extracted from

  • Zhang, Y.; Laing, C.; Zhang, Z.; Hallewell, J.; You, C.; Ziebell, K.; Johnson, R.P.; Kropinski, A.M.; Thomas, J.E.; Karmali, M.; Gannon, V.P.
    Lineage and host source are both correlated with levels of Shiga toxin 2 production by Escherichia coli O157:H7 strains (2010), Appl. Environ. Microbiol., 76, 474-482.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
Stx2 gene, DNA and amino acid sequence determination, genotyping of 117 lineage I, I/II, and II E. coli O157:H7 strains Escherichia coli O157:H7

Protein Variants

Protein Variants Comment Organism
additional information virulence-associated mobile genetic elements, such as Shiga toxin 2-encoding prophage, are lineage restricted or are host source related and acquired independently of the pathogen genotype. DNA sequencing of the stx2 flanking region from a lineage II Escherichia coli O157:H7

Organism

Organism UniProt Comment Textmining
Escherichia coli O157:H7 B6UJ22 Shiga toxin 2c B unit protein, phage LII strains EC970520, F1081, and LS68, and LI/II strain R1388
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Escherichia coli O157:H7 B6UJ28 Shiga toxin 2c A unit protein
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Source Tissue

Source Tissue Comment Organism Textmining
additional information 4 of 14 LI/II phage strains have copies of both stx2 and variant stx2c. LI and LI/II strains produce significantly more stx2 mRNA and Stx2 than LII strains. Among phage LI strains significantly more Stx2 is also produced by strains from humans than from cattle Escherichia coli O157:H7
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Synonyms

Synonyms Comment Organism
Shiga toxin 2
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Escherichia coli O157:H7
Stx2
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Escherichia coli O157:H7