Inhibitors | Comment | Organism | Structure |
---|---|---|---|
scFvC5 | single chain fragment variable antibody, blocks interaction between trichosanthin K173, R174, and K177 residues and ribosomal P proteins protecting ribosomes from inactivation | Trichosanthes kirilowii |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Phytolacca americana | P10297 | isoform pokeweed antiviral protein, i.e. PAP | - |
Trichosanthes kirilowii | P09989 | isoform trichosanthin, i.e. TCS | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
28Sdelta rRNA + H2O | - |
Phytolacca americana | ? | depurination of the A51 residue of Trypanosoma cruzi 28Sdelta rRNA, the C-terminal end of ribosomal P proteins is not required for full activity | ? | |
28Sdelta rRNA + H2O | - |
Trichosanthes kirilowii | ? | depurination of the A51 residue of Trypanosoma cruzi 28Sdelta rRNA, the C-terminal end of ribosomal P proteins is required for full activity of trichosanthin | ? |
Synonyms | Comment | Organism |
---|---|---|
pokeweed antiviral protein | - |
Phytolacca americana |
TCS | - |
Trichosanthes kirilowii |