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Literature summary for 3.2.2.21 extracted from
- Binding of specific DNA base-pair mismatches by N-methylpurine-DNA glycosylase and its implication in initial damage recognition (2002), J. Mol. Biol., 320, 503-513.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| MPG deletion mutant N-DELTA100C-DELTA18 overexpressed in Escherichia coli | Mus musculus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| alkylated DNA + H2O | Mus musculus | binds mismatch base-pairs in DNA | 3-methyladenine + 7-methylguanine + O2-methylthymine + O2-methylcytosine + DNA | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
mouse | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| recombinant protein, expressed in Escherichia coli | Mus musculus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| alkylated DNA + H2O | - |
Mus musculus | 3-methyladenine + 7-methylguanine + O2-methylthymine + O2-methylcytosine + DNA | - |
? | |
| alkylated DNA + H2O | binds mismatch base-pairs in DNA | Mus musculus | 3-methyladenine + 7-methylguanine + O2-methylthymine + O2-methylcytosine + DNA | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| MPG | - |
Mus musculus |
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Release 2023.1 (January 2023)
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