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Literature summary for 3.2.2.21 extracted from

  • Schaerer, O.D.; Ortholand, J.Y.; Ganesan, A.; Ezaz-Nikpay, K.; Verdine, G.L.
    Specific binding of the DNA repair enzyme AlkA to a pyrrolidine-based inhibitor (1995), J. Am. Chem. Soc., 117, 6623-6624.
No PubMed abstract available
Search for more literature for 3.2.2.21

Inhibitors

Inhibitors Comment Organism Structure
Pyrrolidine-containing oligonucleotide
-
 Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
alkylated DNA + H2O Escherichia coli DNA repair enzyme, inducible base excision repair pathway of DNA alkylation damage 3-methyladenine + 7-methylguanine + O2-methylthymine + O2-methylcytosine + DNA
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alkylated DNA + H2O
-
 Escherichia coli 3-methyladenine + 7-methylguanine + O2-methylthymine + O2-methylcytosine + DNA
-
 ?
alkylated DNA + H2O DNA repair enzyme, inducible base excision repair pathway of DNA alkylation damage Escherichia coli 3-methyladenine + 7-methylguanine + O2-methylthymine + O2-methylcytosine + DNA
-
 ?