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Literature summary for 3.2.2.20 extracted from

  • Hasplova, K.; Hudecova, A.; Magdolenova, Z.; Bjoras, M.; Galova, E.; Miadokova, E.; Dusinska, M.
    DNA alkylation lesions and their repair in human cells: Modification of the comet assay with 3-methyladenine DNA glycosylase (AlkD) (2012), Toxicol. Lett., 208, 76-81.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
alkylated DNA + H2O Homo sapiens 50% of DNA alkylation is repaired in the first 60 min after treatment with methyl methanesulfonate 3-methyladenine + ?
-
?
alkylated DNA + H2O Homo sapiens 50% of DNA alkylation is repaired in the first 60 min after treatment with methyl methanesulfonate 7-methylguanine + ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
TK-6 cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alkylated DNA + H2O 50% of DNA alkylation is repaired in the first 60 min after treatment with methyl methanesulfonate Homo sapiens 3-methyladenine + ?
-
?
alkylated DNA + H2O 50% of DNA alkylation is repaired in the first 60 min after treatment with methyl methanesulfonate Homo sapiens 7-methylguanine + ?
-
?

Synonyms

Synonyms Comment Organism
3-methyladenine DNA glycosylase
-
Homo sapiens
AlkD
-
Homo sapiens