Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.2.2.20 extracted from

  • Aamodt, R.M.; Falnes, P.; Johansen, R.F.; Seeberg, E.; Bjoras, M.
    The Bacillus subtilis counterpart of the mammalian 3-methyladenine DNA glycosylase has hypoxanthine and 1,N6,ethenoadenine as preferred substrates (2004), J. Biol. Chem., 279, 13601-13606.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
aag gene cloned in pUC19and expressed in Escherichia coli Bacillus subtilis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
alkylated DNA + H2O Homo sapiens
-
3-methyladenine + ?
-
?
alkylated DNA + H2O Bacillus subtilis important role in preventing the mutagenic effects of deaminated purines and cyclic etheno adducts 3-methyladenine + ?
-
?
alkylated DNA + H2O Bacillus subtilis 168 important role in preventing the mutagenic effects of deaminated purines and cyclic etheno adducts 3-methyladenine + ?
-
?

Organism

Organism UniProt Comment Textmining
Bacillus subtilis
-
-
-
Bacillus subtilis 168
-
-
-
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Homo sapiens
recombinant protein, expressed in Escherichia coli Bacillus subtilis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alkylated DNA + H2O
-
Homo sapiens 3-methyladenine + ?
-
?
alkylated DNA + H2O calf thymus DNA Bacillus subtilis 3-methyladenine + ? prefers to release hypoxanthine and 1,N6,ethenoadenine ?
alkylated DNA + H2O important role in preventing the mutagenic effects of deaminated purines and cyclic etheno adducts Bacillus subtilis 3-methyladenine + ?
-
?
alkylated DNA + H2O calf thymus DNA Bacillus subtilis 168 3-methyladenine + ? prefers to release hypoxanthine and 1,N6,ethenoadenine ?
alkylated DNA + H2O important role in preventing the mutagenic effects of deaminated purines and cyclic etheno adducts Bacillus subtilis 168 3-methyladenine + ?
-
?

Synonyms

Synonyms Comment Organism
bAag
-
Bacillus subtilis
Yx1J
-
Bacillus subtilis