BRENDA - Enzyme Database show
show all sequences of 3.2.2.10

Degradation of pyrimidine nucleotides by enzyme systems of Streptomyces. II. Pyrimidine 5'-nucleotide phophoribo (deoxyribo) hydrolase of Streptomyces virginiae

Imada, A.; J. Gen. Appl. Microbiol. 13, 267-278 (1967)
No PubMed abstract available

Data extracted from this reference:

Inhibitors
Inhibitors
Commentary
Organism
Structure
Ag+
-
Streptomyces virginiae
Cd2+
-
Streptomyces virginiae
Cr3+
-
Streptomyces virginiae
Cu2+
-
Streptomyces virginiae
EDTA
-
Streptomyces virginiae
Hg2+
-
Streptomyces virginiae
KCN
-
Streptomyces virginiae
p-chloromercuribenzoate
-
Streptomyces virginiae
Zn2+
-
Streptomyces virginiae
KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
6.95
-
5'-UMP
-
Streptomyces virginiae
Metals/Ions
Metals/Ions
Commentary
Organism
Structure
Ca2+
-
Streptomyces virginiae
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
pyrimidine 5'-nucleotides + H2O
Streptomyces virginiae
-
?
-
-
?
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Streptomyces virginiae
-
-
-
Streptomyces virginiae IFO 3729
-
-
-
Purification (Commentary)
Commentary
Organism
-
Streptomyces virginiae
Specific Activity [micromol/min/mg]
Specific Activity Minimum [Ámol/min/mg]
Specific Activity Maximum [Ámol/min/mg]
Commentary
Organism
2.5
-
-
Streptomyces virginiae
Storage Stability
Storage Stability
Organism
-4░C, 2 months
Streptomyces virginiae
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5'-CMP + H2O
-
137031
Streptomyces virginiae
cytosine + ribose 5-phosphate
-
137031
Streptomyces virginiae
?
5'-CMP + H2O
-
137031
Streptomyces virginiae IFO 3729
cytosine + ribose 5-phosphate
-
137031
Streptomyces virginiae IFO 3729
?
5'-deoxy CMP + H2O
-
137031
Streptomyces virginiae
cytosine + deoxyribose 5-phosphate
-
137031
Streptomyces virginiae
?
5'-deoxy CMP + H2O
-
137031
Streptomyces virginiae IFO 3729
cytosine + deoxyribose 5-phosphate
-
137031
Streptomyces virginiae IFO 3729
?
5'-deoxy TMP + H2O
-
137031
Streptomyces virginiae
thymine + deoxyribose 5-phosphate
-
137031
Streptomyces virginiae
?
5'-deoxy TMP + H2O
-
137031
Streptomyces virginiae IFO 3729
thymine + deoxyribose 5-phosphate
-
137031
Streptomyces virginiae IFO 3729
?
5'-deoxy UMP + H2O
-
137031
Streptomyces virginiae
uracil + deoxyribose 5-phosphate
-
137031
Streptomyces virginiae
?
5'-deoxy UMP + H2O
-
137031
Streptomyces virginiae IFO 3729
uracil + deoxyribose 5-phosphate
-
137031
Streptomyces virginiae IFO 3729
?
5'-UMP + H2O
-
137031
Streptomyces virginiae
uracil + ribose 5-phosphate
-
137031
Streptomyces virginiae
ir
5'-UMP + H2O
-
137031
Streptomyces virginiae IFO 3729
uracil + ribose 5-phosphate
-
137031
Streptomyces virginiae IFO 3729
ir
pyrimidine 5'-nucleotides + H2O
-
137031
Streptomyces virginiae
?
-
-
-
?
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
7
-
pyrimidine nucleotides
Streptomyces virginiae
pH Stability
pH Stability
pH Stability Maximum
Commentary
Organism
5.5
8.8
-
Streptomyces virginiae
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
Ag+
-
Streptomyces virginiae
Cd2+
-
Streptomyces virginiae
Cr3+
-
Streptomyces virginiae
Cu2+
-
Streptomyces virginiae
EDTA
-
Streptomyces virginiae
Hg2+
-
Streptomyces virginiae
KCN
-
Streptomyces virginiae
p-chloromercuribenzoate
-
Streptomyces virginiae
Zn2+
-
Streptomyces virginiae
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
6.95
-
5'-UMP
-
Streptomyces virginiae
Metals/Ions (protein specific)
Metals/Ions
Commentary
Organism
Structure
Ca2+
-
Streptomyces virginiae
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
pyrimidine 5'-nucleotides + H2O
Streptomyces virginiae
-
?
-
-
?
Purification (Commentary) (protein specific)
Commentary
Organism
-
Streptomyces virginiae
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [Ámol/min/mg]
Specific Activity Maximum [Ámol/min/mg]
Commentary
Organism
2.5
-
-
Streptomyces virginiae
Storage Stability (protein specific)
Storage Stability
Organism
-4░C, 2 months
Streptomyces virginiae
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5'-CMP + H2O
-
137031
Streptomyces virginiae
cytosine + ribose 5-phosphate
-
137031
Streptomyces virginiae
?
5'-CMP + H2O
-
137031
Streptomyces virginiae IFO 3729
cytosine + ribose 5-phosphate
-
137031
Streptomyces virginiae IFO 3729
?
5'-deoxy CMP + H2O
-
137031
Streptomyces virginiae
cytosine + deoxyribose 5-phosphate
-
137031
Streptomyces virginiae
?
5'-deoxy CMP + H2O
-
137031
Streptomyces virginiae IFO 3729
cytosine + deoxyribose 5-phosphate
-
137031
Streptomyces virginiae IFO 3729
?
5'-deoxy TMP + H2O
-
137031
Streptomyces virginiae
thymine + deoxyribose 5-phosphate
-
137031
Streptomyces virginiae
?
5'-deoxy TMP + H2O
-
137031
Streptomyces virginiae IFO 3729
thymine + deoxyribose 5-phosphate
-
137031
Streptomyces virginiae IFO 3729
?
5'-deoxy UMP + H2O
-
137031
Streptomyces virginiae
uracil + deoxyribose 5-phosphate
-
137031
Streptomyces virginiae
?
5'-deoxy UMP + H2O
-
137031
Streptomyces virginiae IFO 3729
uracil + deoxyribose 5-phosphate
-
137031
Streptomyces virginiae IFO 3729
?
5'-UMP + H2O
-
137031
Streptomyces virginiae
uracil + ribose 5-phosphate
-
137031
Streptomyces virginiae
ir
5'-UMP + H2O
-
137031
Streptomyces virginiae IFO 3729
uracil + ribose 5-phosphate
-
137031
Streptomyces virginiae IFO 3729
ir
pyrimidine 5'-nucleotides + H2O
-
137031
Streptomyces virginiae
?
-
-
-
?
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
7
-
pyrimidine nucleotides
Streptomyces virginiae
pH Stability (protein specific)
pH Stability
pH Stability Maximum
Commentary
Organism
5.5
8.8
-
Streptomyces virginiae
Other publictions for EC 3.2.2.10
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [░C]
Temperature Range [░C]
Temperature Stability [░C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [░C] (protein specific)
Temperature Range [░C] (protein specific)
Temperature Stability [░C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
137027
Jyssum
Pyrimidine 5-nucleosidase in N ...
Neisseria meningitidis
APMIS
97
343-346
1989
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
137028
Lestas
Normal levels of ATP, total nu ...
Homo sapiens
Br. J. Haematol.
63
471-476
1986
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
137029
Sakai
-
Distribution of enzymes relate ...
Alcaligenes faecalis, Alcaligenes faecalis AKU 0101, Pseudomonas sp.
Agric. Biol. Chem.
40
1893-1895
1976
-
-
-
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
137030
Bankel
On the metabolic role of thymi ...
Neurospora crassa
FEBS Lett.
71
147-153
1976
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
137031
Imada
-
Degradation of pyrimidine nucl ...
Streptomyces virginiae, Streptomyces virginiae IFO 3729
J. Gen. Appl. Microbiol.
13
267-278
1967
-
-
-
-
-
-
9
1
-
1
-
1
-
3
-
-
1
-
-
-
1
1
11
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
9
-
1
-
1
-
1
-
-
-
1
-
-
1
1
11
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
137032
Imada
-
Degradation of pyrimidine nucl ...
Streptomyces virginiae, Streptomyces virginiae IFO 3729
J. Gen. Appl. Microbiol.
13
255-265
1967
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-