Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(+-)-1-[(9-deazahypoxanthin-9-yl)methyl]azetidine-2-methanol | transition state analogue inhibitor, comparison with inhibition of human and Plasmodium falciparum enzyme | Bos taurus | |
(+-)-1-[(9-deazahypoxanthin-9-yl)methyl]azetidine-2-methanol | transition state analogue inhibitor, comparison with inhibition of bovine and Plasmodium falciparum enzyme | Homo sapiens | |
(+-)-1-[(9-deazahypoxanthin-9-yl)methyl]azetidine-2-methanol | transition state analogue inhibitor, comparison with inhibition of human and bovine enzyme | Plasmodium falciparum | |
1-[(7-benzyloxymethyl-6-tert-butoxy-9-deazapurin-9-yl)methyl] azetidine-3-methanol | transition state analogue inhibitor, comparison with inhibition of human and Plasmodium falciparum enzyme | Bos taurus | |
1-[(7-benzyloxymethyl-6-tert-butoxy-9-deazapurin-9-yl)methyl] azetidine-3-methanol | transition state analogue inhibitor, comparison with inhibition of bovine and Plasmodium falciparum enzyme | Homo sapiens | |
1-[(7-benzyloxymethyl-6-tert-butoxy-9-deazapurin-9-yl)methyl] azetidine-3-methanol | transition state analogue inhibitor, comparison with inhibition of human and bovine enzyme. Ki value above 10 microM | Plasmodium falciparum | |
1-[(9-deazahypoxanthin-9-yl)methyl]azetidine-3,3dimethanol | transition state analogue inhibitor, comparison with inhibition of human and Plasmodium falciparum enzyme | Bos taurus | |
1-[(9-deazahypoxanthin-9-yl)methyl]azetidine-3,3dimethanol | transition state analogue inhibitor, comparison with inhibition of bovine and Plasmodium falciparum enzyme | Homo sapiens | |
1-[(9-deazahypoxanthin-9-yl)methyl]azetidine-3,3dimethanol | transition state analogue inhibitor, comparison with inhibition of human and bovine enzyme, Ki value above 10 microM | Plasmodium falciparum | |
4'-deaza-1'-aza-2'-deoxy-1'-(9-methylene)-immucillin H | i.e. DADMe-ImmH, transition state analogue inhibitor, comparison with inhibition of human and Plasmodium falciparum enzyme | Bos taurus | |
4'-deaza-1'-aza-2'-deoxy-1'-(9-methylene)-immucillin H | i.e. DADMe-ImmH, transition state analogue inhibitor, comparison with inhibition of bovine and Plasmodium falciparum enzyme | Homo sapiens | |
meso-[(9-deazahypoxanthin-9-yl)methyl]azetidine-2,4-dimethanol hydrochloride | transition state analogue inhibitor, comparison with inhibition of human and Plasmodium falciparum enzyme | Bos taurus | |
meso-[(9-deazahypoxanthin-9-yl)methyl]azetidine-2,4-dimethanol hydrochloride | transition state analogue inhibitor, comparison with inhibition of bovine and Plasmodium falciparum enzyme | Homo sapiens | |
meso-[(9-deazahypoxanthin-9-yl)methyl]azetidine-2,4-dimethanol hydrochloride | transition state analogue inhibitor, comparison with inhibition of human and bovine enzyme | Plasmodium falciparum |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Homo sapiens | - |
- |
- |
Plasmodium falciparum | - |
- |
- |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.000000229 | - |
1-[(9-deazahypoxanthin-9-yl)methyl]azetidine-3,3dimethanol | pH 7.0 | Homo sapiens | |
0.00000048 | - |
1-[(7-benzyloxymethyl-6-tert-butoxy-9-deazapurin-9-yl)methyl] azetidine-3-methanol | pH 7.0 | Bos taurus | |
0.000000665 | - |
1-[(9-deazahypoxanthin-9-yl)methyl]azetidine-3,3dimethanol | pH 7.0 | Bos taurus | |
0.000001 | - |
4'-deaza-1'-aza-2'-deoxy-1'-(9-methylene)-immucillin H | pH 7.0 | Bos taurus | |
0.0000011 | - |
4'-deaza-1'-aza-2'-deoxy-1'-(9-methylene)-immucillin H | pH 7.0 | Homo sapiens | |
0.0000018 | - |
(+-)-1-[(9-deazahypoxanthin-9-yl)methyl]azetidine-2-methanol | pH 7.0 | Homo sapiens | |
0.0000018 | - |
(+-)-1-[(9-deazahypoxanthin-9-yl)methyl]azetidine-2-methanol | pH 7.0 | Bos taurus | |
0.0000063 | - |
1-[(7-benzyloxymethyl-6-tert-butoxy-9-deazapurin-9-yl)methyl] azetidine-3-methanol | pH 7.0 | Homo sapiens | |
0.0000129 | - |
meso-[(9-deazahypoxanthin-9-yl)methyl]azetidine-2,4-dimethanol hydrochloride | pH 7.0 | Homo sapiens | |
0.000016 | - |
meso-[(9-deazahypoxanthin-9-yl)methyl]azetidine-2,4-dimethanol hydrochloride | pH 7.0 | Bos taurus |