Literature summary for 3.2.2.1 extracted from

Furneaux, R.H.; Schramm, V.L.; Tyler, P.C.
Transition state analogue inhibitors of protozoan nucleoside hydrolases (1999), Bioorg. Med. Chem., 7, 2599-2606.

Search for more literature for 3.2.2.1

Inhibitors

Inhibitors	Comment	Organism	Structure
(1S)-(1-aminonaphthalen-4-yl)-1,4-dideoxy-1,4-imino-D-ribitol	-	Trypanosoma brucei
(1S)-1-(2,3-diamino-5-pyridyl)-1,4-dideoxy-1,4-imino-D-ribitol	-	Trypanosoma brucei
(1S)-1-(3,4-diaminophenyl)-1,4-dideoxy-1,4-imino-D-ribitol	-	Trypanosoma brucei
(1S)-1-(4-aminomethyl)phenyl-1,4-dideoxy-1,4-imino-D-ribitol	-	Trypanosoma brucei
(1S)-1-(4-cyanophenyl)1,4-dideoxy-1,4-imino-D-ribitol	-	Trypanosoma brucei
1,2,5-trideoxy-1-(guanin-9-yl)-2,5-imino-D-allitol	-	Trypanosoma brucei
1,2,5-trideoxy-1-(hypoxanthin-9-yl)-2,5-imino-D-alitol	-	Trypanosoma brucei
1-(5-carboxamido-2-pyridyl)-1,2,5-trideoxy-2,5-imino-D-allitol	-	Trypanosoma brucei
1-(adenin-9-yl)-1,2,5-trideoxy-2,5-imino-D-allitol	-	Trypanosoma brucei
iminoribitols	poorly inhibited by free or substituted iminoribitols	Trypanosoma brucei
additional information	transition state analogue inhibitors of protozoan nucleoside hydrolases	Trypanosoma brucei

Organism

Organism	UniProt	Comment	Textmining
Trypanosoma brucei	-	brucei	-

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Release 2023.1 (January 2023)