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Literature summary for 3.2.1.B23 extracted from
- Classification of glycosidases that hydrolyze the specific positions and types of sugar moieties in ginsenosides (2016), Crit. Rev. Biotechnol., 36, 1036-1049 .
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ginsenoside C-K + H2O | Rhizobium sp. | - |
protopanaxadiol + D-glucose | - |
? |  |
| ginsenoside C-O + H2O | Bifidobacterium choerinum | - |
ginsenoside F2 + L-arabinopyranose | - |
? | |
| ginsenoside G17 + H2O | Thermus thermophilus | - |
ginsenoside F2 + D-glucose | - |
? | |
| ginsenoside G17 + H2O | Bifidobacterium longum | - |
ginsenoside F2 + D-glucose | - |
? | |
| ginsenoside G17 + H2O | Flavobacterium johnsoniae | - |
ginsenoside F2 + D-glucose | - |
? | |
| ginsenoside G17 + H2O | Bifidobacterium longum H-1 | - |
ginsenoside F2 + D-glucose | - |
? | |
| ginsenoside G75 + H2O | Thermus thermophilus | - |
ginsenoside C-K + D-glucose | - |
? | |
| ginsenoside Mc + H2O | Caldicellulosiruptor saccharolyticus | - |
ginsenoside C-K + L-arabinofuranose | - |
? | |
| ginsenoside Mc + H2O | Rhodanobacter ginsenosidimutans | - |
ginsenoside C-K + L-arabinofuranose | - |
? | |
| ginsenoside Mc1 + H2O | Rhodanobacter ginsenosidimutans | - |
ginsenoside F2 + L-arabinofuranose | - |
? | |
| ginsenoside Rb1 + H2O | Thermus thermophilus | - |
ginsenoside Rd + D-glucose | - |
? | |
| ginsenoside Rb1 + H2O | Trichoderma viride | - |
ginsenoside Rd + D-glucose | - |
? | |
| ginsenoside Rb1 + H2O | Aspergillus sp. | - |
ginsenoside Rd + D-glucose | - |
? | |
| ginsenoside Rb1 + H2O | Bifidobacterium longum | - |
ginsenoside Rd + D-glucose | - |
? | |
| ginsenoside Rb1 + H2O | Lissachatina fulica | - |
ginsenoside Rd + D-glucose | - |
? | |
| ginsenoside Rb1 + H2O | Fulvia fulva | - |
ginsenoside Rd + D-glucose | - |
? | |
| ginsenoside Rb1 + H2O | Pseudothermotoga thermarum | - |
ginsenoside Rd + D-glucose | - |
? | |
| ginsenoside Rb1 + H2O | Flavobacterium johnsoniae | - |
ginsenoside Rd + D-glucose | - |
? | |
| ginsenoside Rb1 + H2O | Aspergillus niger | - |
ginsenoside Rg3 + 2 D-glucose | - |
? | |
| ginsenoside Rb1 + H2O | Pseudonocardia sp. | - |
ginsenoside Rg3 + 2 D-glucose | - |
? | |
| ginsenoside Rb1 + H2O | Microbacterium esteraromaticum | - |
ginsenoside Rg3 + 2 D-glucose | - |
? | |
| ginsenoside Rb1 + H2O | Bifidobacterium longum H-1 | - |
ginsenoside Rd + D-glucose | - |
? | |
| ginsenoside Rb1 + H2O | Pseudothermotoga thermarum DSM 5069T | - |
ginsenoside Rd + D-glucose | - |
? | |
| ginsenoside Rb2 + H2O | Trichoderma viride | - |
ginsenoside Rd + L-arabinofuranose | - |
? | |
| ginsenoside Rb2 + H2O | Bifidobacterium longum | - |
ginsenoside Rd + L-arabinofuranose | - |
? | |
| ginsenoside Rb2 + H2O | Bifidobacterium choerinum | - |
ginsenoside Rd + L-arabinofuranose | - |
? | |
| ginsenoside Rb2 + H2O | Microbacterium esteraromaticum | - |
ginsenoside Rg3 + D-glucose + L-arabinopyranose | - |
? | |
| ginsenoside Rb3 + H2O | Pseudonocardia sp. | - |
ginsenoside Rg3 + D-glucose + D-xylose | - |
? | |
| ginsenoside Rc + H2O | Bifidobacterium breve | - |
ginsenoside Rd + L-arabinofuranose | - |
? | |
| ginsenoside Rc + H2O | Trichoderma viride | - |
ginsenoside Rd + L-arabinofuranose | - |
? | |
| ginsenoside Rc + H2O | Caldicellulosiruptor saccharolyticus | - |
ginsenoside Rd + L-arabinofuranose | - |
? | |
| ginsenoside Rc + H2O | Bifidobacterium longum | - |
ginsenoside Rd + L-arabinofuranose | - |
? | |
| ginsenoside Rc + H2O | Panax ginseng | - |
ginsenoside Rd + L-arabinofuranose | - |
? | |
| ginsenoside Rc + H2O | Leuconostoc sp. | - |
ginsenoside Rd + L-arabinofuranose | - |
? | |
| ginsenoside Rc + H2O | Rhodanobacter ginsenosidimutans | - |
ginsenoside Rd + L-arabinofuranose | - |
? | |
| ginsenoside Rc + H2O | Bifidobacterium longum H-1 | - |
ginsenoside Rd + L-arabinofuranose | - |
? | |
| ginsenoside Rd + H2O | Pseudonocardia sp. | - |
ginsenoside Rg3 + D-glucose | - |
? | |
| ginsenoside Re + H2O | Mucilaginibacter sp. QM49 | - |
ginsenoside Rg2 + D-glucose | - |
? | |
| ginsenoside Rg1 + H2O | Mucilaginibacter sp. QM49 | - |
ginsenoside Rh1 + D-glucose | - |
? | |
| additional information | Thermus thermophilus | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1) | ? | - |
? | |
| additional information | Trichoderma viride | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1) | ? | - |
? | |
| additional information | Aspergillus sp. | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1) | ? | - |
? | |
| additional information | Bifidobacterium longum | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1) | ? | - |
? | |
| additional information | Lissachatina fulica | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1) | ? | - |
? | |
| additional information | Fulvia fulva | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1) | ? | - |
? | |
| additional information | Pseudothermotoga thermarum | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1) | ? | - |
? | |
| additional information | Flavobacterium johnsoniae | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1) | ? | - |
? | |
| additional information | Bifidobacterium breve | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y) | ? | - |
? | |
| additional information | Trichoderma viride | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y) | ? | - |
? | |
| additional information | Caldicellulosiruptor saccharolyticus | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y) | ? | - |
? | |
| additional information | Bifidobacterium longum | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y) | ? | - |
? | |
| additional information | Bifidobacterium choerinum | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y) | ? | - |
? | |
| additional information | Bifidobacterium longum H-1 | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1) | ? | - |
? | |
| additional information | Bifidobacterium longum H-1 | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y) | ? | - |
? | |
| additional information | Pseudothermotoga thermarum DSM 5069T | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1) | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Aspergillus niger | - |
- |
- |
| Aspergillus sp. | - |
- |
- |
| Bifidobacterium breve | - |
- |
- |
| Bifidobacterium choerinum | - |
- |
- |
| Bifidobacterium longum | - |
- |
- |
| Bifidobacterium longum H-1 | - |
- |
- |
| Caldicellulosiruptor saccharolyticus | - |
- |
- |
| Flavobacterium johnsoniae | - |
- |
- |
| Fulvia fulva | - |
- |
- |
| Leuconostoc sp. | - |
- |
- |
| Lissachatina fulica | - |
- |
- |
| Microbacterium esteraromaticum | - |
- |
- |
| Mucilaginibacter sp. QM49 | - |
- |
- |
| Panax ginseng | - |
- |
- |
| Pseudonocardia sp. | - |
- |
- |
| Pseudothermotoga thermarum | - |
- |
- |
| Pseudothermotoga thermarum DSM 5069T | - |
- |
- |
| Rhizobium sp. | - |
- |
- |
| Rhodanobacter ginsenosidimutans | - |
- |
- |
| Thermus thermophilus | - |
- |
- |
| Trichoderma viride | - |
- |
- |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 3 | - |
pH 5.0, 50°C | Panax ginseng |
| 4 | - |
pH 8.0, 30°C | Mucilaginibacter sp. QM49 |
| 5 | - |
pH 6.5, 90°C | Thermus thermophilus |
| 8 | - |
pH 6.8, 37°C | Bifidobacterium longum |
| 9 | - |
pH 5.5, 37°C | Bifidobacterium breve |
| 15 | - |
pH 7.5, 37°C | Rhodanobacter ginsenosidimutans |
| 18 | - |
pH 6.0, 45°C | Fulvia fulva |
| 22 | - |
pH 5.5, 35°C | Bifidobacterium longum |
| 24 | - |
pH 5.5, 45°C | Fulvia fulva |
| 26 | - |
pH 6.0, 37°C | Leuconostoc sp. |
| 28 | - |
pH 5.5, 80°C | Caldicellulosiruptor saccharolyticus |
| 40 | - |
pH 7.0, 37°C | Pseudonocardia sp. |
| 61 | - |
pH 7.0, 40°C | Microbacterium esteraromaticum |
| 67 | - |
pH 4.7, 37°C | Bifidobacterium longum |
| 140 | - |
pH 4.8, 90°C | Pseudothermotoga thermarum |
| 250 | - |
pH 5.6, 70°C | Lissachatina fulica |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ginsenoside C-K + H2O | - |
Rhizobium sp. | protopanaxadiol + D-glucose | - |
? | |
| ginsenoside C-O + H2O | - |
Bifidobacterium choerinum | ginsenoside F2 + L-arabinopyranose | - |
? | |
| ginsenoside G17 + H2O | - |
Thermus thermophilus | ginsenoside F2 + D-glucose | - |
? | |
| ginsenoside G17 + H2O | - |
Bifidobacterium longum | ginsenoside F2 + D-glucose | - |
? | |
| ginsenoside G17 + H2O | - |
Flavobacterium johnsoniae | ginsenoside F2 + D-glucose | - |
? | |
| ginsenoside G17 + H2O | - |
Bifidobacterium longum H-1 | ginsenoside F2 + D-glucose | - |
? | |
| ginsenoside G75 + H2O | - |
Thermus thermophilus | ginsenoside C-K + D-glucose | - |
? | |
| ginsenoside Mc + H2O | - |
Caldicellulosiruptor saccharolyticus | ginsenoside C-K + L-arabinofuranose | - |
? | |
| ginsenoside Mc + H2O | - |
Rhodanobacter ginsenosidimutans | ginsenoside C-K + L-arabinofuranose | - |
? | |
| ginsenoside Mc1 + H2O | - |
Rhodanobacter ginsenosidimutans | ginsenoside F2 + L-arabinofuranose | - |
? | |
| ginsenoside Rb1 + H2O | - |
Thermus thermophilus | ginsenoside Rd + D-glucose | - |
? | |
| ginsenoside Rb1 + H2O | - |
Trichoderma viride | ginsenoside Rd + D-glucose | - |
? | |
| ginsenoside Rb1 + H2O | - |
Aspergillus sp. | ginsenoside Rd + D-glucose | - |
? | |
| ginsenoside Rb1 + H2O | - |
Bifidobacterium longum | ginsenoside Rd + D-glucose | - |
? | |
| ginsenoside Rb1 + H2O | - |
Lissachatina fulica | ginsenoside Rd + D-glucose | - |
? | |
| ginsenoside Rb1 + H2O | - |
Fulvia fulva | ginsenoside Rd + D-glucose | - |
? | |
| ginsenoside Rb1 + H2O | - |
Pseudothermotoga thermarum | ginsenoside Rd + D-glucose | - |
? | |
| ginsenoside Rb1 + H2O | - |
Flavobacterium johnsoniae | ginsenoside Rd + D-glucose | - |
? | |
| ginsenoside Rb1 + H2O | - |
Bifidobacterium longum H-1 | ginsenoside Rd + D-glucose | - |
? | |
| ginsenoside Rb1 + H2O | - |
Pseudothermotoga thermarum DSM 5069T | ginsenoside Rd + D-glucose | - |
? | |
| ginsenoside Rb1 + H2O | - |
Aspergillus niger | ginsenoside Rg3 + 2 D-glucose | - |
? | |
| ginsenoside Rb1 + H2O | - |
Pseudonocardia sp. | ginsenoside Rg3 + 2 D-glucose | - |
? | |
| ginsenoside Rb1 + H2O | - |
Microbacterium esteraromaticum | ginsenoside Rg3 + 2 D-glucose | - |
? | |
| ginsenoside Rb2 + H2O | - |
Trichoderma viride | ginsenoside Rd + L-arabinofuranose | - |
? | |
| ginsenoside Rb2 + H2O | - |
Bifidobacterium longum | ginsenoside Rd + L-arabinofuranose | - |
? | |
| ginsenoside Rb2 + H2O | - |
Bifidobacterium choerinum | ginsenoside Rd + L-arabinofuranose | - |
? | |
| ginsenoside Rb2 + H2O | - |
Microbacterium esteraromaticum | ginsenoside Rg3 + D-glucose + L-arabinopyranose | - |
? | |
| ginsenoside Rb3 + H2O | - |
Pseudonocardia sp. | ginsenoside Rg3 + D-glucose + D-xylose | - |
? | |
| ginsenoside Rc + H2O | - |
Bifidobacterium breve | ginsenoside Rd + L-arabinofuranose | - |
? | |
| ginsenoside Rc + H2O | - |
Trichoderma viride | ginsenoside Rd + L-arabinofuranose | - |
? | |
| ginsenoside Rc + H2O | - |
Caldicellulosiruptor saccharolyticus | ginsenoside Rd + L-arabinofuranose | - |
? | |
| ginsenoside Rc + H2O | - |
Bifidobacterium longum | ginsenoside Rd + L-arabinofuranose | - |
? | |
| ginsenoside Rc + H2O | - |
Panax ginseng | ginsenoside Rd + L-arabinofuranose | - |
? | |
| ginsenoside Rc + H2O | - |
Leuconostoc sp. | ginsenoside Rd + L-arabinofuranose | - |
? | |
| ginsenoside Rc + H2O | - |
Rhodanobacter ginsenosidimutans | ginsenoside Rd + L-arabinofuranose | - |
? | |
| ginsenoside Rc + H2O | - |
Bifidobacterium longum H-1 | ginsenoside Rd + L-arabinofuranose | - |
? | |
| ginsenoside Rd + H2O | - |
Pseudonocardia sp. | ginsenoside Rg3 + D-glucose | - |
? | |
| ginsenoside Re + H2O | - |
Mucilaginibacter sp. QM49 | ginsenoside Rg2 + D-glucose | - |
? | |
| ginsenoside Rg1 + H2O | - |
Mucilaginibacter sp. QM49 | ginsenoside Rh1 + D-glucose | - |
? | |
| additional information | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1) | Thermus thermophilus | ? | - |
? | |
| additional information | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1) | Trichoderma viride | ? | - |
? | |
| additional information | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1) | Aspergillus sp. | ? | - |
? | |
| additional information | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1) | Bifidobacterium longum | ? | - |
? | |
| additional information | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1) | Lissachatina fulica | ? | - |
? | |
| additional information | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1) | Fulvia fulva | ? | - |
? | |
| additional information | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1) | Pseudothermotoga thermarum | ? | - |
? | |
| additional information | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1) | Flavobacterium johnsoniae | ? | - |
? | |
| additional information | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y) | Bifidobacterium breve | ? | - |
? | |
| additional information | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y) | Trichoderma viride | ? | - |
? | |
| additional information | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y) | Caldicellulosiruptor saccharolyticus | ? | - |
? | |
| additional information | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y) | Bifidobacterium longum | ? | - |
? | |
| additional information | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y) | Bifidobacterium choerinum | ? | - |
? | |
| additional information | hydrolysis of the C-20 inner Glc | Aspergillus niger | ? | - |
? | |
| additional information | hydrolysis of the C-20 inner Glc | Pseudonocardia sp. | ? | - |
? | |
| additional information | hydrolysis of the C-20 inner Glc | Rhizobium sp. | ? | - |
? | |
| additional information | hydrolysis of the C-20 inner Glc | Microbacterium esteraromaticum | ? | - |
? | |
| additional information | hydrolysis of the C-20 inner Glc | Mucilaginibacter sp. QM49 | ? | - |
? | |
| additional information | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1) | Bifidobacterium longum H-1 | ? | - |
? | |
| additional information | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y) | Bifidobacterium longum H-1 | ? | - |
? | |
| additional information | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1. Ginsenosidase type II-i-1 catalyze hydrolysis of C-20 outer Glc (hydrolysis pattern A-1) | Pseudothermotoga thermarum DSM 5069T | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 56000 | Rhodanobacter ginsenosidimutans |
| ? | x * 57000 | Bifidobacterium longum |
| ? | x * 57000 | Pseudothermotoga thermarum |
| ? | x * 49000 | Thermus thermophilus |
| ? | x * 58000 | Caldicellulosiruptor saccharolyticus |
| ? | x * 58000 | Leuconostoc sp. |
| ? | x * 80000 | Caldicellulosiruptor saccharolyticus |
| ? | x * 80000 | Fulvia fulva |
| ? | x * 88000 | Microbacterium esteraromaticum |
| ? | x * 60000 | Aspergillus sp. |
| ? | x * 86000 | Panax ginseng |
| ? | x * 120000 | Lissachatina fulica |
| ? | x * 77000 | Bifidobacterium breve |
| ? | x * 79000 | Pseudonocardia sp. |
| ? | x * 81000 | Bifidobacterium longum |
| ? | x * 82000 | Flavobacterium johnsoniae |
| ? | x * 85000 | Mucilaginibacter sp. QM49 |
| ? | x * 87000 | Microbacterium esteraromaticum |
| ? | x * 90000 | Fulvia fulva |
| ? | x * 95000 | Bifidobacterium longum |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| alpha-L-arabinofuranosidase | - |
Caldicellulosiruptor saccharolyticus |
| alpha-L-arabinofuranosidase | - |
Bifidobacterium longum |
| alpha-L-arabinofuranosidase | - |
Panax ginseng |
| alpha-L-arabinofuranosidase | - |
Leuconostoc sp. |
| alpha-L-arabinofuranosidase | - |
Rhodanobacter ginsenosidimutans |
| alpha-L-arabinopyranosidase | - |
Bifidobacterium breve |
| alpha-L-arabinopyranosidase | - |
Caldicellulosiruptor saccharolyticus |
| alpha-L-arabinopyranosidase | - |
Bifidobacterium longum |
| beta-galactosidase | - |
Caldicellulosiruptor saccharolyticus |
| beta-glucosidase | - |
Thermus thermophilus |
| beta-glucosidase | - |
Pseudonocardia sp. |
| beta-glucosidase | - |
Aspergillus sp. |
| beta-glucosidase | - |
Microbacterium esteraromaticum |
| beta-glucosidase | - |
Bifidobacterium longum |
| beta-glucosidase | - |
Lissachatina fulica |
| beta-glucosidase | - |
Pseudothermotoga thermarum |
| beta-glucosidase | - |
Flavobacterium johnsoniae |
| beta-glucosidase | - |
Mucilaginibacter sp. QM49 |
| beta-glucosidase GI | - |
Fulvia fulva |
| beta-glucosidase GII | - |
Fulvia fulva |
| ginsenosidase type II | - |
Thermus thermophilus |
| ginsenosidase type II | - |
Aspergillus niger |
| ginsenosidase type II | - |
Pseudonocardia sp. |
| ginsenosidase type II | - |
Rhizobium sp. |
| ginsenosidase type II | - |
Bifidobacterium breve |
| ginsenosidase type II | - |
Trichoderma viride |
| ginsenosidase type II | - |
Aspergillus sp. |
| ginsenosidase type II | - |
Caldicellulosiruptor saccharolyticus |
| ginsenosidase type II | - |
Microbacterium esteraromaticum |
| ginsenosidase type II | - |
Bifidobacterium longum |
| ginsenosidase type II | - |
Lissachatina fulica |
| ginsenosidase type II | - |
Panax ginseng |
| ginsenosidase type II | - |
Fulvia fulva |
| ginsenosidase type II | - |
Leuconostoc sp. |
| ginsenosidase type II | - |
Pseudothermotoga thermarum |
| ginsenosidase type II | - |
Flavobacterium johnsoniae |
| ginsenosidase type II | - |
Bifidobacterium choerinum |
| ginsenosidase type II | - |
Rhodanobacter ginsenosidimutans |
| ginsenosidase type II | - |
Mucilaginibacter sp. QM49 |
| ginsenosidase type II-i-1 | - |
Thermus thermophilus |
| ginsenosidase type II-i-1 | - |
Trichoderma viride |
| ginsenosidase type II-i-1 | - |
Aspergillus sp. |
| ginsenosidase type II-i-1 | - |
Bifidobacterium longum |
| ginsenosidase type II-i-1 | - |
Lissachatina fulica |
| ginsenosidase type II-i-1 | - |
Fulvia fulva |
| ginsenosidase type II-i-1 | - |
Pseudothermotoga thermarum |
| ginsenosidase type II-i-1 | - |
Flavobacterium johnsoniae |
| ginsenosidase type II-i-2 | - |
Bifidobacterium breve |
| ginsenosidase type II-i-2 | - |
Trichoderma viride |
| ginsenosidase type II-i-2 | - |
Caldicellulosiruptor saccharolyticus |
| ginsenosidase type II-i-2 | - |
Bifidobacterium longum |
| ginsenosidase type II-i-2 | - |
Bifidobacterium choerinum |
| ginsenosidase type II-i-4 | - |
Trichoderma viride |
| ginsenosidase type II-i-4 | - |
Caldicellulosiruptor saccharolyticus |
| ginsenosidase type II-i-4 | - |
Bifidobacterium longum |
| ginsenosidase type II-i-4 | - |
Panax ginseng |
| ginsenosidase type II-i-4 | - |
Leuconostoc sp. |
| ginsenosidase type II-i-4 | - |
Rhodanobacter ginsenosidimutans |
| ginsenosidase type II-ii | - |
Aspergillus niger |
| ginsenosidase type II-ii | - |
Pseudonocardia sp. |
| ginsenosidase type II-ii | - |
Rhizobium sp. |
| ginsenosidase type II-ii | - |
Microbacterium esteraromaticum |
| ginsenosidase type II-ii | - |
Mucilaginibacter sp. QM49 |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 30 | - |
- |
Mucilaginibacter sp. QM49 |
| 35 | - |
- |
Bifidobacterium longum |
| 37 | - |
- |
Pseudonocardia sp. |
| 37 | - |
- |
Bifidobacterium breve |
| 37 | - |
- |
Bifidobacterium longum |
| 37 | - |
- |
Leuconostoc sp. |
| 37 | - |
- |
Flavobacterium johnsoniae |
| 37 | - |
- |
Rhodanobacter ginsenosidimutans |
| 40 | - |
- |
Microbacterium esteraromaticum |
| 45 | - |
- |
Fulvia fulva |
| 50 | - |
- |
Aspergillus sp. |
| 50 | - |
- |
Panax ginseng |
| 70 | - |
- |
Lissachatina fulica |
| 80 | - |
- |
Caldicellulosiruptor saccharolyticus |
| 90 | - |
- |
Thermus thermophilus |
| 90 | - |
- |
Pseudothermotoga thermarum |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 4.7 | - |
- |
Bifidobacterium longum |
| 4.8 | - |
- |
Pseudothermotoga thermarum |
| 5 | - |
- |
Aspergillus sp. |
| 5 | - |
- |
Panax ginseng |
| 5.5 | - |
- |
Bifidobacterium breve |
| 5.5 | - |
- |
Caldicellulosiruptor saccharolyticus |
| 5.5 | - |
- |
Bifidobacterium longum |
| 5.5 | - |
- |
Fulvia fulva |
| 5.6 | - |
- |
Lissachatina fulica |
| 6 | - |
- |
Caldicellulosiruptor saccharolyticus |
| 6 | - |
- |
Fulvia fulva |
| 6 | - |
- |
Leuconostoc sp. |
| 6 | - |
- |
Flavobacterium johnsoniae |
| 6.5 | - |
- |
Thermus thermophilus |
| 6.8 | - |
- |
Bifidobacterium longum |
| 7 | - |
- |
Pseudonocardia sp. |
| 7 | - |
- |
Microbacterium esteraromaticum |
| 7.5 | - |
- |
Rhodanobacter ginsenosidimutans |
| 8 | - |
- |
Mucilaginibacter sp. QM49 |
General Information
| General Information | Comment | Organism |
|---|---|---|
| evolution | the enzyme belongs to the glycosyl hydrolase family 1, GH1 | Thermus thermophilus |
| evolution | the enzyme belongs to the glycosyl hydrolase family 1, GH1 | Pseudothermotoga thermarum |
| evolution | the enzyme belongs to the glycosyl hydrolase family 2, GH2 | Microbacterium esteraromaticum |
| evolution | the enzyme belongs to the glycosyl hydrolase family 3, GH3 | Pseudonocardia sp. |
| evolution | the enzyme belongs to the glycosyl hydrolase family 3, GH3 | Microbacterium esteraromaticum |
| evolution | the enzyme belongs to the glycosyl hydrolase family 3, GH3 | Bifidobacterium longum |
| evolution | the enzyme belongs to the glycosyl hydrolase family 3, GH3 | Flavobacterium johnsoniae |
| evolution | the enzyme belongs to the glycosyl hydrolase family 3, GH3 | Mucilaginibacter sp. QM49 |
| evolution | the enzyme belongs to the glycosyl hydrolase family 42, GH42 | Caldicellulosiruptor saccharolyticus |
| evolution | the enzyme belongs to the glycosyl hydrolase family 51, GH51 | Caldicellulosiruptor saccharolyticus |
| evolution | the enzyme belongs to the glycosyl hydrolase family 51, GH51 | Bifidobacterium longum |
| evolution | the enzyme belongs to the glycosyl hydrolase family 51, GH51 | Leuconostoc sp. |
| evolution | the enzyme belongs to the glycosyl hydrolase family 51, GH51 | Rhodanobacter ginsenosidimutans |
| physiological function | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2 | Trichoderma viride |
| physiological function | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2 | Caldicellulosiruptor saccharolyticus |
| physiological function | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2 | Bifidobacterium longum |
| physiological function | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2 | Panax ginseng |
| physiological function | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2 | Leuconostoc sp. |
| physiological function | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2 | Rhodanobacter ginsenosidimutans |
| physiological function | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y) | Bifidobacterium breve |
| physiological function | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y) | Trichoderma viride |
| physiological function | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y) | Caldicellulosiruptor saccharolyticus |
| physiological function | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y) | Bifidobacterium longum |
| physiological function | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y) | Bifidobacterium choerinum |
| physiological function | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides with 4 different hydrolysis patterns | Thermus thermophilus |
| physiological function | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides with 4 different hydrolysis patterns | Trichoderma viride |
| physiological function | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides with 4 different hydrolysis patterns | Aspergillus sp. |
| physiological function | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides with 4 different hydrolysis patterns | Bifidobacterium longum |
| physiological function | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides with 4 different hydrolysis patterns | Lissachatina fulica |
| physiological function | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides with 4 different hydrolysis patterns | Fulvia fulva |
| physiological function | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides with 4 different hydrolysis patterns | Pseudothermotoga thermarum |
| physiological function | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides with 4 different hydrolysis patterns | Flavobacterium johnsoniae |
| physiological function | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-ii. Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively. Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides | Aspergillus niger |
| physiological function | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-ii. Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively. Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides | Pseudonocardia sp. |
| physiological function | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-ii. Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively. Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides | Rhizobium sp. |
| physiological function | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-ii. Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively. Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides | Microbacterium esteraromaticum |
| physiological function | ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-ii. Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively. Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides | Mucilaginibacter sp. QM49 |
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Release 2023.1 (January 2023)
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