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Literature summary for 3.2.1.76 extracted from
- alpha-L-iduronidase and arylsulfatase B in dried blood spots on filter paper Biochemical parameters and time stability (2017), Clin. Biochem., 50, 431-435.
General Stability
| General Stability | Organism |
|---|---|
| the enzyme activity significantly decayes starting at 21 days after the filter paper was impregnated with blood | Homo sapiens |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 1.48 | - |
4-methylumbelliferyl alpha-L-iduronide | at pH 2.8 and 37°C | Homo sapiens |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | P35475 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-methylumbelliferyl alpha-L-iduronide + H2O | - |
Homo sapiens | 4-methylumbelliferone + alpha-L-iduronic acid | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| alpha-L-iduronidase | - |
Homo sapiens |
| IDUA | - |
Homo sapiens |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 2.8 | - |
- |
Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | mucopolysaccharidosis type I is caused by the deficient activity of the enzyme | Homo sapiens |
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