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Literature summary for 3.2.1.76 extracted from

  • Wynn, R.F.; Mercer, J.; Page, J.; Carr, T.F.; Jones, S.; Wraith, J.E.
    Use of enzyme replacement therapy (Laronidase) before hematopoietic stem cell transplantation for mucopolysaccharidosis I: experience in 18 patients (2009), J. Pediatr., 154, 135-139.
    View publication on PubMed

Application

Application Comment Organism
medicine the benefit of enzyme replacement therapy with recombinant laronidase before hematopoietic stem cell transplantation for mucopolysaccharidosis I is linked to improvement in patient's pretransplantation condition and thus tolerance of such intensive therapy. Short-term use of laronidase is not associated with increased risk of either graft-versus-host-disease or graft failure Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Synonyms

Synonyms Comment Organism
Aldurazyme
-
Homo sapiens
alpha-L-iduronidase
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Homo sapiens
laronidase
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Homo sapiens