Literature summary for 3.2.1.52 extracted from

Dudzik, D.; Knas, M.; Gocal, M.; Borzym-Kluczyk, M.; Szajda, S.D.; Knas-Karaszewska, K.; Tomaszewski, J.; Zwierz, K.
Activity of N-acetyl-beta-D-hexosaminidase (HEX) and its isoenzymes A and B in human milk during the first 3 months of breastfeeding (2008), Adv. Med. Sci., 53, 300-304.

Search for more literature for 3.2.1.52

Activating Compound

Activating Compound	Comment	Organism	Structure
additional information	total HEX activity increases by the 100th day after postpartum as compared to the 21st day after postpartum. Activity of HEX B significantly increases by the 100th day of lactation as compared to the 21st day	Homo sapiens

Application

Application	Comment	Organism
medicine	HEX and its isoenzymes' activity significantly correlate with the progression of lactation	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	total HEX activity decreases by the 21st day of lactation in comparison to the 3rd day after postpartum. Total HEX activity significantly decreases by the 100th day of lactation, as compared to milk taken on the 3rd day of lactation. Activity of HEX A significantly decreases by the 21st and 100th day of lactation as compared to the 3rd day of lactation. The activity of HEX B significantly decreases on the 21st day of lactation as compared to activity in milk obtained on the 3rd day, and tends to decrease at the 100th day of lactation in comparison to the 3rd day	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
milk	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	at the beginning of lactation, HEX A activity, which releases hexosamines from acidic oligosaccharides, dominates. Later, HEX B releases hexosamines from neutral oligosaccharides	Homo sapiens	?	-	?

Synonyms

Synonyms	Comment	Organism
Hex A	-	Homo sapiens
Hex B	-	Homo sapiens
N-acetyl-beta-D-hexosaminidase	-	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)