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Literature summary for 3.2.1.51 extracted from
- Comparative stuy of alpha-L-fucosidase from three species os marine molluscs: Purification and properties (1979), Glycoconjugate Res., 2, 867-871.
No PubMed abstract available
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| alpha-L-fucose | competitive inhibition at 50 mM | Chamelea gallina |  |
| alpha-L-fucose | competitive inhibition at 50 mM | Littorina littorea | |
| alpha-L-fucose | competitive inhibition at 50 mM | Polititapes rhomboides | |
| Hg2+ | effective non-competitive inhibition at 2 mM | Chamelea gallina | |
| Hg2+ | effective non-competitive inhibition at 2 mM | Littorina littorea | |
| Hg2+ | effective non-competitive inhibition at 2 mM | Polititapes rhomboides | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.07 | - |
4-nitrophenyl-alpha-L-fucopyranoside | - |
Chamelea gallina | |
| 0.14 | - |
4-nitrophenyl-alpha-L-fucopyranoside | - |
Polititapes rhomboides | |
| 0.3 | - |
4-nitrophenyl-alpha-L-fucopyranoside | - |
Littorina littorea | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 200000 | - |
gel filtration | Chamelea gallina |
| 200000 | - |
gel filtration | Polititapes rhomboides |
| 220000 | - |
gel filtration | Littorina littorea |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| oligosaccharide + H2O | Littorina littorea | di-, tri- and pentasaacharides having alpha-1-2, alpha-1-3, and alpha-1-4 bonds | alpha-L-fucose + ? | - |
? | |
| oligosaccharide + H2O | Chamelea gallina | di-, tri- and pentasaacharides having alpha-1-2, alpha-1-3, and alpha-1-4 bonds | alpha-L-fucose + ? | - |
? | |
| submaxillary mucin + H2O | Littorina littorea | A-minus type and desialyzed, porcine | alpha-L-fucose + ? | - |
? | |
| submaxillary mucin + H2O | Chamelea gallina | A-minus type and desialyzed, porcine | alpha-L-fucose + ? | - |
? | |
| thyroglobulin + H2O | Littorina littorea | - |
alpha-L-fucose + ? | - |
? | |
| thyroglobulin + H2O | Chamelea gallina | - |
alpha-L-fucose + ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Chamelea gallina | - |
- |
- |
| Littorina littorea | - |
- |
- |
| Polititapes rhomboides | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| glycoprotein | contains 7.4% glucose, 2.2% galactose, 1.8% mannose, 2.2% hexosamine | Littorina littorea |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| to homogeneity, isoelectric focusing | Littorina littorea |
| to homogeneity, isoelectric focusing | Chamelea gallina |
| to homogeneity, isoelectric focusing | Polititapes rhomboides |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| hepatopancreas | - |
Littorina littorea | - |
| hepatopancreas | - |
Chamelea gallina | - |
| hepatopancreas | - |
Polititapes rhomboides | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-nitrophenyl-alpha-L-fucopyranoside + H2O | - |
Littorina littorea | 4-nitrophenol + alpha-L-fucose | - |
? | |
| 4-nitrophenyl-alpha-L-fucopyranoside + H2O | - |
Chamelea gallina | 4-nitrophenol + alpha-L-fucose | - |
? | |
| 4-nitrophenyl-alpha-L-fucopyranoside + H2O | - |
Polititapes rhomboides | 4-nitrophenol + alpha-L-fucose | - |
? | |
| oligosaccharide + H2O | di-, tri- and pentasaacharides having alpha-1-2, alpha-1-3, and alpha-1-4 bonds | Littorina littorea | alpha-L-fucose + ? | - |
? | |
| oligosaccharide + H2O | di-, tri- and pentasaacharides having alpha-1-2, alpha-1-3, and alpha-1-4 bonds | Chamelea gallina | alpha-L-fucose + ? | - |
? | |
| oligosaccharides + H2O | di-, tri- and pentasaacharides having alpha-1-2, alpha-1-3, and alpha-1-4 bonds | Littorina littorea | alpha-L-fucose + ? | - |
? | |
| oligosaccharides + H2O | di-, tri- and pentasaacharides having alpha-1-2, alpha-1-3, and alpha-1-4 bonds | Chamelea gallina | alpha-L-fucose + ? | - |
? | |
| submaxillary mucin + H2O | A-minus type and desialyzed, porcine | Littorina littorea | alpha-L-fucose + ? | - |
? | |
| submaxillary mucin + H2O | A-minus type and desialyzed, porcine | Chamelea gallina | alpha-L-fucose + ? | - |
? | |
| thyroglobulin + H2O | - |
Littorina littorea | alpha-L-fucose + ? | - |
? | |
| thyroglobulin + H2O | - |
Chamelea gallina | alpha-L-fucose + ? | - |
? | |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 60 | - |
fully active for 5 min | Littorina littorea |
| 60 | - |
fully active for 5 min | Chamelea gallina |
| 60 | - |
fully active for 5 min | Polititapes rhomboides |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 5.2 | - |
- |
Chamelea gallina |
| 5.3 | - |
- |
Polititapes rhomboides |
| 6.5 | - |
- |
Littorina littorea |
pH Stability
| pH Stability | pH Stability Maximum | Comment | Organism |
|---|---|---|---|
| 4 | 6 | stable between | Chamelea gallina |
| 4 | 6 | stable between | Polititapes rhomboides |
| 5 | 8 | stable between | Littorina littorea |
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