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Literature summary for 3.2.1.51 extracted from

  • DiCioccio, R.A.; Barlow, J.J.; Matta, K.L.
    Substrate specificity and other properties of alpha-L-fucosidase from human serum (1982), J. Biol. Chem., 257, 714-718.
    View publication on PubMed
Search for more literature for 3.2.1.51

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.18
-
 4-nitrophenyl-alpha-L-fucopyranoside
-
 Homo sapiens
0.52
-
 Fuc-alpha-(1-2)-Gal-beta-4-nitrophenol
-
 Homo sapiens
1.56
-
 Fuc-alpha-(1-2)-Gal-beta-(1-4)-Glc
-
 Homo sapiens
1.63
-
 Fuc-alpha-(1-3)-GlcNAc-phenol
-
 Homo sapiens
2.01
-
 Fuc-alpha-(1-4)-GlcNAc-beta-phenol
-
 Homo sapiens
2.9
-
 Fuc-alpha-(1-2)-Gal
-
 Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
270000
-
 gel filtration at pH 7.0 Homo sapiens
390000
-
 gel filtration at pH 5.0 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Fuc-alpha-(1-2)-Gal + H2O Homo sapiens
-
 alpha-L-fucose + D-galactose
-
 ?
Fuc-alpha-(1-2)-Gal-beta-(1-4)-Glc + H2O Homo sapiens 2'-fucosyllactose alpha-L-fucose + lactose
-
 ?
Fuc-alpha-(1-2)-Glc + H2O Homo sapiens
-
 alpha-L-fucose + D-glucose
-
 ?
Fuc-alpha-(1-2)-Xyl + H2O Homo sapiens
-
 alpha-L-fucose + D-xylose
-
 ?
Fuc-alpha-(1-3)-Gal + H2O Homo sapiens
-
 alpha-L-fucose + D-galactose
-
 ?
Fuc-alpha-(1-3)-Glc + H2O Homo sapiens
-
 alpha-L-fucose + D-glucose
-
 ?
Fuc-alpha-(1-3)-GlcNAc + H2O Homo sapiens
-
 alpha-L-fucose + N-acetyl-D-glucosamine
-
 ?
Fuc-alpha-(1-4)-GlcNAc + H2O Homo sapiens
-
 alpha-L-fucose + N-acetyl-D-glucosamine
-
 ?
Fuc-alpha-(1-6)-Gal + H2O Homo sapiens
-
 alpha-L-fucose + D-galactose
-
 ?
Fuc-alpha-(1-6)-GlcNAc + H2O Homo sapiens
-
 alpha-L-fucose + N-acetyl-D-glucosamine
-
 ?
Fuc-alpha-(1-6)-GlcNAc-beta-Asn + H2O Homo sapiens
-
 alpha-L-fucose + N-acetyl-D-glucosaminyl-Asn
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
to homogeneity, affinity chromatography Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
serum
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
10.66
-
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-nitrophenyl-alpha-L-fucopyranoside + H2O
-
 Homo sapiens 4-nitrophenol + alpha-L-fucose
-
 ?
Fuc-alpha-(1-2)-Fuc-beta-4-nitrophenol + H2O
-
 Homo sapiens alpha-L-fucose + Fuc-beta-4-nitrophenol
-
 ?
Fuc-alpha-(1-2)-Gal + H2O
-
 Homo sapiens alpha-L-fucose + D-galactose
-
 ?
Fuc-alpha-(1-2)-Gal-beta-(1-3)-GalNAc-alpha-phenol + H2O
-
 Homo sapiens alpha-L-fucose + Gal-beta-(1-3)-N-acetyl-galactosaminyl-phenol
-
 ?
Fuc-alpha-(1-2)-Gal-beta-(1-4)-Glc + H2O 2'-fucosyllactose Homo sapiens alpha-L-fucose + lactose
-
 ?
Fuc-alpha-(1-2)-Gal-beta-4-nitrophenol + H2O
-
 Homo sapiens alpha-L-fucose + beta-galactosyl-4-nitrophenol
-
 ?
Fuc-alpha-(1-2)-Glc + H2O
-
 Homo sapiens alpha-L-fucose + D-glucose
-
 ?
Fuc-alpha-(1-2)-Xyl + H2O
-
 Homo sapiens alpha-L-fucose + D-xylose
-
 ?
Fuc-alpha-(1-2)-[Gal-alpha-(1-3)]-Gal-beta-phenol + H2O
-
 Homo sapiens alpha-L-fucose + Gal-alpha-(1-3)-Gal-beta-phenol
-
 ?
Fuc-alpha-(1-3)-Gal + H2O
-
 Homo sapiens alpha-L-fucose + D-galactose
-
 ?
Fuc-alpha-(1-3)-Glc + H2O
-
 Homo sapiens alpha-L-fucose + D-glucose
-
 ?
Fuc-alpha-(1-3)-GlcNAc + H2O
-
 Homo sapiens alpha-L-fucose + N-acetyl-D-glucosamine
-
 ?
Fuc-alpha-(1-3)-GlcNAc-beta-O(CH2)6NHCOCF3 + H2O
-
 Homo sapiens alpha-L-fucose + GlcNAc-beta-O(CH2)6NHCOCF3
-
 ?
Fuc-alpha-(1-3)-GlcNAc-beta-phenol + H2O
-
 Homo sapiens alpha-L-fucose + N-acetyl-glucosaminyl-beta-phenol
-
 ?
Fuc-alpha-(1-3)-GlcNAc-phenol + H2O
-
 Homo sapiens alpha-L-fucose + N-acetyl-glucosaminyl-beta-phenol
-
 ?
Fuc-alpha-(1-4)-GlcNAc + H2O
-
 Homo sapiens alpha-L-fucose + N-acetyl-D-glucosamine
-
 ?
Fuc-alpha-(1-4)-GlcNAc-beta-phenol + H2O
-
 Homo sapiens alpha-L-fucose + beta-N-acetyl-glucosaminyl-phenol
-
 ?
Fuc-alpha-(1-4)-[Gal-beta-(1-3)]-GlcNAc-beta-phenol + H2O
-
 Homo sapiens alpha-L-fucose + Gal-beta-(1-3)-GlcNAc-beta-phenol
-
 ?
Fuc-alpha-(1-6)-Gal + H2O
-
 Homo sapiens alpha-L-fucose + D-galactose
-
 ?
Fuc-alpha-(1-6)-GlcNAc + H2O
-
 Homo sapiens alpha-L-fucose + N-acetyl-D-glucosamine
-
 ?
Fuc-alpha-(1-6)-GlcNAc-4-nitrophenol + H2O
-
 Homo sapiens alpha-L-fucose + GlcNAc-4-nitrophenol
-
 ?
Fuc-alpha-(1-6)-GlcNAc-beta-Asn + H2O
-
 Homo sapiens alpha-L-fucose + N-acetyl-D-glucosaminyl-Asn
-
 ?
Fuc-alpha-(1-6)-[Gal-beta-(1-3)]-GlcNAc-beta-OCH3 + H2O
-
 Homo sapiens alpha-L-fucose + Gal-beta-(1-3)-GlcNAc-beta-OCH3
-
 ?

Subunits

Subunits Comment Organism
oligomer contains subunits of 63 kDa, SDS-PAGE Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5
-
-
 Homo sapiens