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Literature summary for 3.2.1.49 extracted from

  • Mohamad, S.B.; Nagasawa, H.; Uto, Y.; Hori, H.
    Tumor cell alpha-N-acetylgalactosaminidase activity and its involvement in GcMAF-related macrophage activation (2002), Comp. Biochem. Physiol. A, 132, 1-8.
    View publication on PubMed
Search for more literature for 3.2.1.49

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
Chang liver cell
-
 Homo sapiens
-
HCT-116 cell
-
 Homo sapiens
-
Hep-G2 cell
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.0012
-
 pH 5.0, Chang liver cell Homo sapiens
0.0021
-
 pH 5.0, Hep-G2 cell Homo sapiens
0.0026
-
 pH 5.0, HCT116 cell Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information Gal-beta-GalNAc-alpha-PNP is no substrate for Hep-G2 cell lysate, the enzyme of tumor cell lysate reduces the macrophage activing potency of GcMAF Homo sapiens ?
-
 ?
p-nitrophenyl-alpha-N-acetyl-D-galactoaminide + H2O the Hep-G2 cell lysate hydrolyzes the exo-type substrate Homo sapiens p-nitrophenol + alpha-N-acetyl-D-galactosamine
-
 ?

Synonyms

Synonyms Comment Organism
alpha-NaGalase
-
 Homo sapiens

pH Stability

pH Stability pH Stability Maximum Comment Organism
additional information
-
 comparison of activity at pH 5.0, 6.0 and 7.0 from Hep-G2 cells, HCT116 cells and Chang liver cells Homo sapiens