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Literature summary for 3.2.1.48 extracted from

  • Sigrist, H.; Ronner, P.; Semenza, G.
    A hydrophobic form of the small-intestinal sucrase-isomaltase complex (1975), Biochim. Biophys. Acta, 406, 433-446.
    View publication on PubMed
Search for more literature for 3.2.1.48

Inhibitors

Inhibitors Comment Organism Structure
Tris concentration-dependent biphasic effect, first causing activation, fully competitive inhibition above pH 6.8, inhibition is stronger at alkaline pH values Oryctolagus cuniculus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
8.4
-
 sucrose
-
 Oryctolagus cuniculus

Metals/Ions

Metals/Ions Comment Organism Structure
Na+ low concentration: activation Oryctolagus cuniculus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
140000
-
 SDS-PAGE, sucrase-isomaltase Oryctolagus cuniculus
220000
-
-
 Oryctolagus cuniculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
maltose + H2O Oryctolagus cuniculus
-
 2 glucose
-
 ?
sucrose + H2O Oryctolagus cuniculus
-
 D-glucose + D-fructose
-
 ?

Organism

Organism UniProt Comment Textmining
Oryctolagus cuniculus
-
 rabbit
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.1
-
-
 Oryctolagus cuniculus
17.5
-
-
 Oryctolagus cuniculus

Storage Stability

Storage Stability Organism
4°C or -20°C, 0.02% sodium azide, Triton X-100, several weeks, sucrase-isomaltase Oryctolagus cuniculus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
maltose + H2O
-
 Oryctolagus cuniculus 2 glucose
-
 ?
sucrose + H2O
-
 Oryctolagus cuniculus D-glucose + D-fructose
-
 ?