Cloned (Comment) | Organism |
---|---|
expressed in Chinese hamster ovary cells and in transgenic carrot cells | Homo sapiens |
Crystallization (Comment) | Organism |
---|---|
velaglucerase alfa, micro-batch crystallization under oil, using 1 M (NH4)2SO4/0.1 M HEPES, pH 7.0, containing 0.5% (w/v) PEG8000 | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.015 | - |
glucosylceramide | imiglucerase, in 50 mM sodium citrate, pH 6.0 with 0.75 mg/ml bovine serum albumin, at 37°C | Homo sapiens | |
0.019 | - |
glucosylceramide | velaglucerase alfa, in 50 mM sodium citrate, pH 6.0 with 0.75 mg/ml bovine serum albumin, at 37°C | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P04062 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
glucosylceramide + H2O | - |
Homo sapiens | beta-D-glucose + ceramide | - |
? |
Synonyms | Comment | Organism |
---|---|---|
acid-beta-glucocerebrosidase | - |
Homo sapiens |
acid-beta-glucosidase | - |
Homo sapiens |
Cerezyme | commercial preparation | Homo sapiens |
gene-activated human GlcCerase | commercial preparation | Homo sapiens |
GlcCerase | - |
Homo sapiens |
Imiglucerase | - |
Homo sapiens |
velaglucerase alfa | commercial preparation | Homo sapiens |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
31.67 | - |
glucosylceramide | imiglucerase alfa, in 50 mM sodium citrate, pH 6.0 with 0.75 mg/ml bovine serum albumin, at 37°C | Homo sapiens | |
35 | - |
glucosylceramide | velaglucerase alfa, in 50 mM sodium citrate, pH 6.0 with 0.75 mg/ml bovine serum albumin, at 37°C | Homo sapiens |