Literature summary for 3.2.1.45 extracted from

Sinclair, G.; Choy, F.Y.
Synonymous codon usage bias and the expression of human glucocerebrosidase in the methylotrophic yeast, Pichia pastoris (2002), Protein Expr. Purif., 26, 96-105.

Search for more literature for 3.2.1.45

Application

Application	Comment	Organism
medicine	an inherited deficiency in this enzyme leads to the onset of Gaucher disease	Homo sapiens

Cloned(Commentary)

Cloned (Comment)	Organism
using fragments of the enzyme cDNA fused to the luciferase c DNA as a translational read-through reporter, the impact of synonymous codon usage bias on protein expression in Pichia pastoris as a potential system for the high-level heterologous production of human enzyme	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Homo sapiens	the enzyme catalyses the penultimate step in the breakdown of membrane glycosphingolipids	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	the enzyme catalyses the penultimate step in the breakdown of membrane glycosphingolipids	Homo sapiens	?	-	?

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Release 2023.1 (January 2023)