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Literature summary for 3.2.1.45 extracted from
- Molecular and cell biology of acid beta-glucosidase and prosaposin (2001), Prog. Nucleic Acid Res. Mol. Biol., 66, 203-239.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| phosphatidylinositol | acidic, unsaturated phospholipid interfaces interact with acid beta-glucosidase to conform the enzyme into an active structure | Homo sapiens |  |
| phosphatidylserine | acidic, unsaturated phospholipid interfaces interact with acid beta-glucosidase to conform the enzyme into an active structure | Homo sapiens | |
| saposin C | required for full activity reconstruction of pure enzyme, study of saposin C, acidic, unsaturated phospholipid and enzyme interaction | Homo sapiens | |
| Triton X-100 | - |
Homo sapiens | |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Homo sapiens |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | more than 200 natural occurring mutations are identified in patients with Gaucher disease | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Homo sapiens |
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