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Literature summary for 3.2.1.45 extracted from

  • Leonova, T.; Grabowski, G.A.
    Fate and sorting of acid beta-glucosidase in transgenic mammalian cells (2000), Mol. Genet. Metab., 70, 281-294.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
Phospholipid the full catalytic activity requires phospholipid interfaces Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
overexpression in CHO cells, transfected with the tetracycline transactivation conditional expression system, majority of enzyme is secreted and overexpression in C2C12 cells, transducted with MFG-enzyme retrovirus Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
64000
-
endo-H-sensitive form, expressed in CHO cell Homo sapiens
69000
-
endo-H-resistant form, expressed in CHO cell Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
fibroblast normal fibroblasts and fibroblasts of patients with Gaucher disease Homo sapiens
-

Synonyms

Synonyms Comment Organism
acid beta-glycosidase
-
Homo sapiens
Gcase
-
Homo sapiens