Activating Compound | Comment | Organism | Structure |
---|---|---|---|
saposin-C | activation varies depending on mutation | Homo sapiens | |
sodium taurocholate | - |
Homo sapiens |
Application | Comment | Organism |
---|---|---|
medicine | Gaucher disease, sphingolipoidose | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
2.1 | 3.7 | 4-methylumbelliferyl-beta-D-glucopyranoside | different patients | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
glucocerebroside + H2O | Homo sapiens | - |
glucose + ceramide | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
normal and Gaucher disease enzyme | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
fibroblast | skin fibroblasts in culture | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-methylumbelliferyl-beta-D-glucopyranoside + H2O | - |
Homo sapiens | methylumbelliferone + glucose | - |
? | |
6(N-methyl-N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl))aminohexyl-2-N-sphingosyl 1-O-beta-D-glucoside + H2O | NBD-glucocerebroside | Homo sapiens | D-glucose + 6(N-methyl-N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl))aminohexyl-2-N-sphingosine | - |
? | |
6(N-methyl-N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl))aminohexyl-2-N-sphingosyl 1-O-beta-D-glucoside + H2O | complexed with bovine serum albumin | Homo sapiens | D-glucose + 6(N-methyl-N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl))aminohexyl-2-N-sphingosine | - |
? | |
glucocerebroside + H2O | - |
Homo sapiens | glucose + ceramide | - |
? |