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Literature summary for 3.2.1.35 extracted from
- High-resolution hyaluronidase inhibition profiling combined with HPLC-HRMS-SPE-NMR for identification of anti-necrosis constituents in Chinese plants used to treat snakebite (2015), Phytochemistry, 119, 62-69 .
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| aristolochic acid | - |
Deinagkistrodon acutus |  |
| aristolochic acid | - |
Naja atra | |
| lansiumamide B | - |
Deinagkistrodon acutus | |
| myricetin 3-O-beta-D-glucopyranoside | - |
Naja atra | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Deinagkistrodon acutus | - |
- |
- |
| Gloydius brevicaudus | - |
- |
- |
| Naja atra | - |
- |
- |
| Trimeresurus stejnegeri | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| venom | - |
Naja atra | - |
| venom | - |
Deinagkistrodon acutus | - |
| venom | - |
Trimeresurus stejnegeri | - |
| venom | - |
Gloydius brevicaudus | - |
IC50 Value
| IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|
| 0.18 | - |
pH and temperature not specified in the publication | Deinagkistrodon acutus | aristolochic acid | |
| 0.22 | - |
pH and temperature not specified in the publication | Deinagkistrodon acutus | lansiumamide B | |
| 0.29 | - |
pH and temperature not specified in the publication | Naja atra | aristolochic acid | |
| 0.56 | - |
pH and temperature not specified in the publication | Naja atra | myricetin 3-O-beta-D-glucopyranoside | |
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