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Literature summary for 3.2.1.35 extracted from

  • Jung, Y.; Jung, M.Y.; Park, J.H.; Jung, G.C.; Hong, Y.S.; Yeom, C.H.; Lee, S.
    Production of human hyaluronidase in a plant-derived protein expression system: plant-based transient production of active human hyaluronidase (2010), Protein Expr. Purif., 74, 181-188.
    View publication on PubMed
Search for more literature for 3.2.1.35

Cloned(Commentary)

Cloned (Comment) Organism
transient expression in Nicotiana benthamiana Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens O43820
-
-
Homo sapiens Q12794
-
-
Homo sapiens Q12891
-
-
Homo sapiens Q2M3T9
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein
-
 Homo sapiens

Purification (Commentary)

Purification (Comment) Organism
recombinant protein Homo sapiens

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.08
-
 pH 3.5, 37°C Homo sapiens
1.5
-
 pH 7.1, 37°C Homo sapiens
1.55
-
 pH 7.1, 37°C Homo sapiens
2.4
-
 pH 3.5, 37°C Homo sapiens
22.6
-
 pH 3.5, 37°C Homo sapiens
61.15
-
 pH 3.5, 37°C Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-S-chondroitin sulfate + H2O
-
 Homo sapiens ?
-
 ?
6-S-chondroitin sulfate + H2O
-
 Homo sapiens ?
-
 ?
hyaluronic acid + H2O
-
 Homo sapiens ?
-
 ?
additional information among hyaluronidases Hyal-1 to Hyal-4, only rHuHyal-4 exhibits chondroitinase activity with both 6-S-chondroitin sulfate and 4-S-chondroitin sulfate as standard substrates Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
Hyal-1
-
 Homo sapiens
Hyal-2
-
 Homo sapiens
Hyal-3
-
 Homo sapiens
Hyal-4
-
 Homo sapiens
LUCA-1
-
 Homo sapiens
LUCA-2
-
 Homo sapiens
Luca-3
-
 Homo sapiens