Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3-amino-6-chloro-N-(diaminomethylidene)-5-[ethyl(propan-2-yl)amino]pyrazine-2-carboxamide | - |
Rattus norvegicus | |
dimethyl sulfoxide | - |
Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cell surface | Hyal2 is partly expressed at the cell surface | Rattus norvegicus | 9986 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
52000 | - |
SDS-PAGE | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | Q9Z2Q3 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
Rat-1/BB16 cell | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
hyaluronan + 2 H2O | - |
Rattus norvegicus | N-acetyl-beta-D-glucosamine + D-glucuronate + ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Hyal2 | - |
Rattus norvegicus |
hyaluronidase-2 | - |
Rattus norvegicus |
General Information | Comment | Organism |
---|---|---|
physiological function | Hyal2, through direct interactions with CD44 and possibly some pericellular hyaluronidase activity requiring acidic foci, suppresses the formation or the stability of the glycocalyx, modulates ezrin-radixin-moesin-related cytoskeletal interactions, and diminishes cell motility | Rattus norvegicus |