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Literature summary for 3.2.1.35 extracted from
- bFGF induces changes in hyaluronan synthase and hyaluronidase isoform expression and modulates the migration capacity of fibrosarcoma cells (2009), Biochim. Biophys. Acta, 1790, 1258-1265.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| hyaluronan + 2 H2O | Homo sapiens | - |
N-acetyl-beta-D-glucosamine + D-glucuronate + ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | Q12794 | - |
- |
| Homo sapiens | Q12891 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| HT-1080 cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| hyaluronan + 2 H2O | - |
Homo sapiens | N-acetyl-beta-D-glucosamine + D-glucuronate + ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| HYAL1 | isoform | Homo sapiens |
| Hyal2 | isoform | Homo sapiens |
| hyaluronidase-1 | isoform | Homo sapiens |
| hyaluronidase-2 | isoform | Homo sapiens |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Homo sapiens | basic fibroblast growth factor decreases hyaluronidase-2 expression in HT-1080 cells | down |
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Release 2023.1 (January 2023)
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