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Literature summary for 3.2.1.35 extracted from

  • Feng, L.; Gao, R.; Gopalakrishnakone, P.
    Isolation and characterization of a hyaluronidase from the venom of Chinese red scorpion Buthus martensi (2008), Comp. Biochem. Physiol. C, 148, 250-257.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
additional information the expression of CD44v6 is reduced when MDA-MB-231 cancer cells are treated with BmHYA1 for 48 h Mesobuthus martensii

Inhibitors

Inhibitors Comment Organism Structure
Cu2+
-
Mesobuthus martensii
DTT
-
Mesobuthus martensii
Fe3+
-
Mesobuthus martensii
heparin
-
Mesobuthus martensii

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
48696
-
x * 48696, using MALDI-TOF Mesobuthus martensii
48700
-
using MALDI-TOF Mesobuthus martensii

Organism

Organism UniProt Comment Textmining
Mesobuthus martensii P86100
-
-

Purification (Commentary)

Purification (Comment) Organism
using successive chromatography: gel filtration, anion exchange chromatography, cation exchange chromatography, reversed-phase HPLC Mesobuthus martensii

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
hyaluronan + H2O
-
Mesobuthus martensii ?
-
?

Subunits

Subunits Comment Organism
? x * 48696, using MALDI-TOF Mesobuthus martensii

Synonyms

Synonyms Comment Organism
BmHYA1
-
Mesobuthus martensii
hyaluronidase
-
Mesobuthus martensii

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
assay at Mesobuthus martensii
50
-
optimal activity Mesobuthus martensii

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
4.5
-
-
Mesobuthus martensii