Application | Comment | Organism |
---|---|---|
medicine | as major hyaluronidases in human cells, HYAL1 and HYAL2 may control intercellular interactions and microenvironment of tumour cells providing excellent targets for cancer treatment | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
- |
Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | this gene may play an important role in the development of lung and renal malignancies, the expression of hyaluronidase-1 or hyaluronidase-2 suppresses tumour growth in vivo but not in vitro, HYAL2 inhibits experimental lung metastases in nu/nu mice | ? | - |
? | |
additional information | Homo sapiens | this gene may play an important role in the development of lung and renal malignancies, the expression of hyaluronidase-1 suppresses tumour growth in vivo but not in vitro | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q12794 | HYAL1 gene of the the LUCA region | - |
Homo sapiens | Q12891 | HYAL2 gene of the the LUCA region | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | this gene may play an important role in the development of lung and renal malignancies, the expression of hyaluronidase-1 or hyaluronidase-2 suppresses tumour growth in vivo but not in vitro, HYAL2 inhibits experimental lung metastases in nu/nu mice | Homo sapiens | ? | - |
? | |
additional information | this gene may play an important role in the development of lung and renal malignancies, the expression of hyaluronidase-1 suppresses tumour growth in vivo but not in vitro | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
hyaluronidase-1 | - |
Homo sapiens |
hyaluronidase-2 | - |
Homo sapiens |
hyaluronoglucosaminidase 1 | - |
Homo sapiens |
hyaluronoglucosaminidase 2 | - |
Homo sapiens |