Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.2.1.31 extracted from

  • Ueyama, J.; Satoh, T.; Kondo, T.; Takagi, K.; Shibata, E.; Goto, M.; Kimata, A.; Saito, I.; Hasegawa, T.; Wakusawa, S.; Kamijima, M.
    beta-Glucuronidase activity is a sensitive biomarker to assess low-level organophosphorus insecticide exposure (2010), Toxicol. Lett., 193, 115-119.
    View publication on PubMed
Search for more literature for 3.2.1.31

Activating Compound

Activating Compound Comment Organism Structure
chlorpyrifos-methyl
-
 Homo sapiens
diazinon
-
 Homo sapiens
dichlorvos
-
 Homo sapiens
fenitrothion
-
 Homo sapiens
fenthion
-
 Homo sapiens
additional information organophosphorous insecticides lead to several fold increased plasma enzyme activity, overview Homo sapiens
propetamphos
-
 Homo sapiens

Application

Application Comment Organism
diagnostics beta-glucuronidase activity is a sensitive biomarker to assess low-level organophosphorus insecticide exposure, e.g. plasma BG activity for low-level organophosphorus-exposure compared to BChE activity, overview Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
-
 Homo sapiens
-
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 male adults
-

Source Tissue

Source Tissue Comment Organism Textmining
blood plasma
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-methylumbelliferyl-beta-D-glucuronide + H2O
-
 Homo sapiens 4-methylumbelliferol + D-glucuronate
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
4.6
-
 assay at Homo sapiens