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Literature summary for 3.2.1.31 extracted from

  • Contractor, S.F.; Shane, B.
    Purification and characterization of lysosomal -glucuronidase from human placenta (1972), Biochem. J., 128, 11-18.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.2.1.31

Activating Compound

Activating Compound Comment Organism Structure
bovine serum albumin activation Homo sapiens
Plasma serum acivation Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
inhibitor heat stable, competetive, in plasma Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.018 3.08 phenolphthalein beta-D-glucuronide dependency on pH Homo sapiens
0.041 1.3 4-methylumbelliferyl-beta-D-glucuronide
-
 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
lysosome
-
 Homo sapiens 5764
-
microsome
-
 Homo sapiens
-
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
placenta
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
phenolphthalein beta-D-glucuronide + H2O
-
 Homo sapiens phenolphthalein + D-glucuronic acid
-
 ?

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
70
-
 lysosomal form: 60 min, 80% activity, plasma enzyme: 15 min, 0% activity Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
3
-
 substrate 4-methylumbelliferyl-beta-D-glucuronide Homo sapiens
5
-
-
 Homo sapiens