Cloned (Comment) | Organism |
---|---|
expression in COS cells | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-deoxymannojirimicin | IC50 = 0.01 mM | Mus musculus | |
Co2+ | slight inhibition at 1 mM | Mus musculus | |
EDTA | complete inhibition at 0.05 mM | Mus musculus | |
Mn2+ | slight inhibition at 1 mM | Mus musculus | |
Zn2+ | complete inhibition at 1 mM | Mus musculus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | requirement for divalent cations with preference for Ca2+ | Mus musculus | |
Mg2+ | slight activation at 1 mM | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Man7GlcNAc + 2 H2O | Mus musculus | - |
Man5GlcNAc + 2 alpha-D-mannopyranose | - |
? | |
Man8GlcNAc + 3 H2O | Mus musculus | - |
Man5GlcNAc + 3 alpha-D-mannopyranose | - |
? | |
Man9GlcNAc + 4 H2O | Mus musculus | - |
Man5GlcNAc + 4 alpha-D-mannopyranose | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
recombinant protein, immobilized on IgG Sepharose | Mus musculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Man7GlcNAc + 2 H2O | - |
Mus musculus | Man5GlcNAc + 2 alpha-D-mannopyranose | - |
? | |
Man8GlcNAc + 3 H2O | - |
Mus musculus | Man5GlcNAc + 3 alpha-D-mannopyranose | - |
? | |
Man9GlcNAc + 4 H2O | - |
Mus musculus | Man5GlcNAc + 4 alpha-D-mannopyranose | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Golgi mannosidase IB | - |
Mus musculus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.5 | - |
- |
Mus musculus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.01 | - |
IC50 = 0.01 mM | Mus musculus | 1-deoxymannojirimicin |