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Literature summary for 3.2.1.207 extracted from
- Partial purification and biochemical characterization of a soluble alpha-glucosidase II-like activity from Candida albicans (2004), FEMS Microbiol. Lett., 236, 123-128 .
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 1-deoxynojirimycin | 0.01 mM, 60% inhibition | Candida albicans |  |
| 6-deoxy-D-glucose | - |
Candida albicans | |
| australine | 0.01 mM, 20% inhibition | Candida albicans | |
| bromoconduritol | 0.01 mM, 40% inhibition | Candida albicans | |
| castanospermine | 0.01 mM, 10% inhibition | Candida albicans | |
| D-glucose | - |
Candida albicans | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.055 | - |
4-methylumbellyferyl alpha-D-glucopyranoside | pH 7.5, 37°C | Candida albicans | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Candida albicans | Q2V621 | - |
- |
| Candida albicans ATCC 26555 | Q2V621 | - |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial | Candida albicans |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-methylumbellyferyl alpha-D-glucopyranoside + H2O | - |
Candida albicans | 4-methylumbelliferone + D-glucose | - |
? | |
| 4-methylumbellyferyl alpha-D-glucopyranoside + H2O | - |
Candida albicans ATCC 26555 | 4-methylumbelliferone + D-glucose | - |
? | |
| GlcMan9GlcNAc2 + H2O | - |
Candida albicans | D-glucose + Man9GlcNAc2 | - |
? | |
| GlcMan9GlcNAc2 + H2O | - |
Candida albicans ATCC 26555 | D-glucose + Man9GlcNAc2 | - |
? | |
| nigerose + H2O | - |
Candida albicans | 2 D-glucose | - |
? | |
| nigerose + H2O | - |
Candida albicans ATCC 26555 | 2 D-glucose | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 47000, SDS-PAGE | Candida albicans |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CWH41 | - |
Candida albicans |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
- |
Candida albicans |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.5 | - |
- |
Candida albicans |
IC50 Value
| IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|
| 0.4 | - |
pH 7.5, 37°C | Candida albicans | 6-deoxy-D-glucose | |
| 1.3 | - |
pH 7.5, 37°C | Candida albicans | D-glucose | |
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