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Literature summary for 3.2.1.20 extracted from
- Alpha-amylase and alpha-glucosidase inhibition is differentially modulated by fucoidan obtained from Fucus vesiculosus and Ascophyllum nodosum (2014), Phytochemistry, 98, 27-33.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| fucoidan | fucoidan derived from algal species Ascophyllum nodosum and Fucus vesiculosus. Fucoidan extracted from Ascophyllum nodosum is a more potent inhibitor of alpha-glucosidase. Fucoidan extracted from Fucus vesiculosus does not inhibit a-amylase activity, EC 3.2.1.1, while fucoidan from Ascophyllum nodosum decreases alpha-amylase activity by 7-100% at 5 mg/ml | Saccharomyces cerevisiae |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Saccharomyces cerevisiae | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| commercial preparation | - |
Saccharomyces cerevisiae | - |
IC50 Value
| IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|
| additional information | - |
Fucoidan extracted from Ascophyllum nodosum, IC50 ranging from 0.013 to 0.047 mg/ml, fucoidan extracted from Fucus vesiculosus, IC50 0.049 mg/ml, pH 6.8, 37°C | Saccharomyces cerevisiae | fucoidan | |
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Release 2023.1 (January 2023)
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