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Literature summary for 3.2.1.20 extracted from

  • Lam, S.H.; Chen, J.M.; Kang, C.J.; Chen, C.H.; Lee, S.S.
    alpha-Glucosidase inhibitors from the seeds of Syagrus romanzoffiana (2008), Phytochemistry, 69, 1173-1178.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
13-hydroxykompasinol A isolated from seeds of Syagrus romanzoffiana Geobacillus stearothermophilus
3,3',4,5,5'-pentahydroxy-trans-stilbene isolated from seeds of Syagrus romanzoffiana Geobacillus stearothermophilus
4-hydroxybenzoic acid isolated from seeds of Syagrus romanzoffiana Geobacillus stearothermophilus
kompasinol A isolated from seeds of Syagrus romanzoffiana Geobacillus stearothermophilus
additional information defatted EtOH extract of the seeds of Syagrus romanzoffiana shows 55% inhibitory activity against alpha-glucosidase at a concentration of 0.010 mg/ml, inhibitor structure determination by NMR, overview Geobacillus stearothermophilus
piceatannol isolated from seeds of Syagrus romanzoffiana Geobacillus stearothermophilus
resveratrol isolated from seeds of Syagrus romanzoffiana Geobacillus stearothermophilus
scirpusin A isolated from seeds of Syagrus romanzoffiana Geobacillus stearothermophilus
scirpusin C isolated from seeds of Syagrus romanzoffiana Geobacillus stearothermophilus

Organism

Organism UniProt Comment Textmining
Geobacillus stearothermophilus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
commercial preparation
-
Geobacillus stearothermophilus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-nitrophenyl alpha-D-glucopyranoside + H2O
-
Geobacillus stearothermophilus 4-nitrophenol + alpha-D-glucose
-
?

Synonyms

Synonyms Comment Organism
alpha-glucosidase type IV
-
Geobacillus stearothermophilus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
assay at Geobacillus stearothermophilus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.5
-
assay at Geobacillus stearothermophilus

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.0049
-
pH 6.5, 37°C Geobacillus stearothermophilus scirpusin C
0.0065
-
pH 6.5, 37°C Geobacillus stearothermophilus 13-hydroxykompasinol A
0.0083
-
pH 6.5, 37°C Geobacillus stearothermophilus scirpusin A
0.0112
-
pH 6.5, 37°C Geobacillus stearothermophilus kompasinol A
0.0192
-
pH 6.5, 37°C Geobacillus stearothermophilus 3,3',4,5,5'-pentahydroxy-trans-stilbene
0.0232
-
pH 6.5, 37°C Geobacillus stearothermophilus piceatannol
0.0239
-
pH 6.5, 37°C Geobacillus stearothermophilus resveratrol
0.0564
-
pH 6.5, 37°C Geobacillus stearothermophilus 4-hydroxybenzoic acid