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Literature summary for 3.2.1.20 extracted from

  • Quezada-Calvillo, R.; Robayo-Torres, C.C.; Opekun, A.R.; Sen, P.; Ao, Z.; Hamaker, B.R.; Quaroni, A.; Brayer, G.D.; Wattler, S.; Nehls, M.C.; Sterchi, E.E.; Nichols, B.L.
    Contribution of mucosal maltase-glucoamylase activities to mouse small intestinal starch alpha-glucogenesis (2007), J. Nutr., 137, 1725-1733.
    View publication on PubMed
Search for more literature for 3.2.1.20

Cloned(Commentary)

Cloned (Comment) Organism
genotyping of wild-type and mutant enzymes, cDNA sequencing of the Mgam null mice Mus musculus

Protein Variants

Protein Variants Comment Organism
additional information ablation of maltase-glucoamylase gene expression by homologous recombination in Sv/129 mice, genotyping and phenotyping, overview Mus musculus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information kinetics of wild-type, mutant and null mutant mice Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane bound Mus musculus 16020
-
soluble
-
 Mus musculus
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1,4-alpha-D-glucooligosaccharide + H2O Mus musculus the four isozymes digest all linear starch oligosaccharides to glucose alpha-D-glucose
-
 ?
maltose + H2O Mus musculus
-
 alpha-D-glucose + D-glucose
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus Q6XK23 fragment
-
Mus musculus Q6XK24 fragment
-

Source Tissue

Source Tissue Comment Organism Textmining
enterocyte 4 isozymes bound to the luminal surface of enterocytes, 2 isozymes are associated with sucrase-isomaltase activities Mus musculus
-
jejunum mucosa Mus musculus
-
mucosa
-
 Mus musculus
-
small intestine mucosa Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1,4-alpha-D-glucooligosaccharide + H2O the four isozymes digest all linear starch oligosaccharides to glucose Mus musculus alpha-D-glucose
-
 ?
maltose + H2O
-
 Mus musculus alpha-D-glucose + D-glucose
-
 ?

Synonyms

Synonyms Comment Organism
maltase
-
 Mus musculus
maltase-glucoamylase
-
 Mus musculus
MGAM
-
 Mus musculus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Mus musculus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.8
-
 assay at Mus musculus