Literature summary for 3.2.1.20 extracted from

Luo, J.G.; Ma, L.; Kong, L.Y.
New triterpenoid saponins with strong alpha-glucosidase inhibitory activity from the roots of Gypsophila oldhamiana (2008), Bioorg. Med. Chem., 16, 2912-2920.

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Inhibitors

Inhibitors	Comment	Organism	Structure
3-keto,16alpha-hydroxy,24-noroleanolic acid	-	Saccharomyces cerevisiae
3-keto,16alpha-hydroxy,24-noroleanolic acid 28-O-alpha-L-arabinopyranosyl-(1-4)-alpha-L-arabinopyranosyl-(1-3)-beta-D-xylopyranosyl-(1-4)-alpha-L-rhamnopyranosyl-(1-2)-beta-D-fucopyranosyl ester	-	Saccharomyces cerevisiae
3-O-beta-D-galactopyranosyl-(1-2)-beta-D-glucuronopyranosyl gypsogenin 28-O-beta-D-xylopyranosyl-(1-4)-alpha-Lrhamnopyranosyl-(1-2)-beta-D-fucopyranoside	-	Saccharomyces cerevisiae
3-O-beta-D-galactopyranosyl-(1-2)-[beta-D-xylopyranosyl-(1-3)]-beta-D-glucuronopyranosyl gypsogenin 28-O-(6-O-acetyl)-beta-D-glucopyranosyl-(1-3)-[beta-D-xylopyranosyl-(1-4)]-alpha-L-rhamnopyranosyl-(1-2)-beta-D-fucopyranoside	-	Saccharomyces cerevisiae
3-O-beta-D-galactopyranosyl-(1-2)-[beta-D-xylopyranosyl-(1-3)]-beta-D-glucuronopyranosyl gypsogenin 28-O-alpha-L-arabinopyranosyl-(1-3)-beta-D-xylopyranosyl-(1-4)-alpha-L-rhamnopyranosyl-(1-2)-beta-D-fucopyranoside	-	Saccharomyces cerevisiae
gypsogenin	-	Saccharomyces cerevisiae
gypsogenin 28-O-alpha-D-galactopyranosyl-(1-6)-beta-D-glucopyranosyl-(1-6)-[beta-D-glucopyranosyl-(1-3)]-beta-D-glucopyranosyl ester	-	Saccharomyces cerevisiae
additional information	NMR structure determination and inhibitory activity of triterpenoid saponin inhibitors isolated from the roots of Gypsophila oldhamiana used in traditional Chinese medicine, overview	Saccharomyces cerevisiae
quillaic acid	-	Saccharomyces cerevisiae
quillaic acid 3-O-beta-D-galactopyranosyl-(1-2)-[beta-D-galactopyranosyl-(1-3)]-beta-D-glucuronopyranoside	-	Saccharomyces cerevisiae
segetalic acid 28-O-alpha-L-arabinopyranosyl-(1-4)-alpha-L-arabinopyranosyl-(1-3)-beta-D-xylopyranosyl-(1-4)-alpha-L-rhamnopyranosyl-(1-2)-beta-D-fucopyranosyl ester	-	Saccharomyces cerevisiae

Organism

Organism	UniProt	Comment	Textmining
Saccharomyces cerevisiae	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
commercial preparation	-	Saccharomyces cerevisiae	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4-nitrophenyl alpha-D-glucopyranoside + H2O	-	Saccharomyces cerevisiae	4-nitrophenol + alpha-D-glucose	-	?

Temperature Optimum [°C]

Temperature Optimum [°C]	Temperature Optimum Maximum [°C]	Comment	Organism
37	-	assay at	Saccharomyces cerevisiae

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
6.8	-	assay at	Saccharomyces cerevisiae

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Release 2023.1 (January 2023)