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Literature summary for 3.2.1.183 extracted from

  • Stäsche, R.; Hinderlich, S.; Weise, C.; Effertz, K.; Lucka, L.; Moormann, P.; Reutter, W.
    A bifunctional enzyme catalyzes the first two steps in N-acetylneuraminic acid biosynthesis of rat liver. Molecular cloning and functional expression of UDP-N-acetyl-glucosamine 2-epimerase/N-acetylmannosamine kinase (1997), J. Biol. Chem., 272, 24319-24324.
    View publication on PubMed
Search for more literature for 3.2.1.183

Cloned(Commentary)

Cloned (Comment) Organism
recombinant bifunctional enzyme is expressed in COS7 cells Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Rattus norvegicus 5829
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
79000
-
 calculated from cDNA Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
intestinal mucosa
-
 Rattus norvegicus
-
liver
-
 Rattus norvegicus
-
salivary gland
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-N-acetyl-alpha-D-glucosamine + H2O
-
 Rattus norvegicus N-acetyl-alpha-D-mannosamine + UDP
-
 ?

Synonyms

Synonyms Comment Organism
UDP-GlcNAc 2-epimerase bifunctional enzyme exhibiting UDP-N-acetylglucosamine 2-epimerase and N-acetylmannosamine kinase activity Rattus norvegicus
UDP-N-acetylglucosamine 2-epimerase
-
 Rattus norvegicus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Rattus norvegicus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.5
-
 assay at Rattus norvegicus