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Literature summary for 3.2.1.18 extracted from

  • Hata, K.; Tochigi, T.; Sato, I.; Kawamura, S.; Shiozaki, K.; Wada, T.; Takahashi, K.; Moriya, S.; Yamaguchi, K.; Hosono, M.; Miyagi, T.
    Increased sialidase activity in serum of cancer patients Identification of sialidase and inhibitor activities in human serum (2015), Cancer Sci., 106, 383-389 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.2.1.18

Cloned(Commentary)

Cloned (Comment) Organism
expressed in HEK-293 T cells Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
exosome
-
 Homo sapiens
-
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
octyl-Sepharose chromatography and Toyopearl HW-55F column chromatography Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
serum
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-methylumbelliferyl alpha-D-N-acetylneuraminic acid + H2O about 1% activity compared to ganglioside GD3 Homo sapiens 4-methylumbelliferone + alpha-D-N-acetylneuraminic acid
-
 ?
fetuin + H2O about 5% activity compared to ganglioside GD3 Homo sapiens ?
-
 ?
ganglioside GD3 + H2O 100% activity Homo sapiens N-acetylneuraminate + ganglioside GM3
-
 ?
ganglioside GM3 + H2O about 60% activity compared to ganglioside GD3 Homo sapiens N-acetylneuraminate + beta-D-galactosyl-(1->4)-beta-D-glucosylceramide
-
 ?
siallyllactose + H2O about 7% activity compared to ganglioside GD3 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
Neu3
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens the enzyme activity is increased in serum of prostate cancer patients up