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Literature summary for 3.2.1.18 extracted from

  • Hunter, C.D.; Khanna, N.; Richards, M.R.; Rezaei Darestani, R.; Zou, C.; Klassen, J.S.; Cairo, C.W.
    Human neuraminidase isoenzymes show variable activities for 9-O-acetyl-sialoside substrates (2018), ACS Chem. Biol., 13, 922-932 .
    View publication on PubMed
Search for more literature for 3.2.1.18

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21(DE3) cells Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
Ni-NTA column chromatography, and Superdex 200 gel filtration Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
HEK-293E cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2'-(4-methylumbelliferyl) 9-O-acetyl-alpha-D-N-acetylneuraminic acid + H2O
-
 Homo sapiens 4-methyl-umbelliferone + 9-O-acetyl-alpha-D-N-acetylneuraminic acid
-
 ?
2'-(4-methylumbelliferyl) alpha-D-N-acetylneuraminic acid + H2O
-
 Homo sapiens 4-methyl-umbelliferone + alpha-D-N-acetylneuraminic acid
-
 ?
2'-(4-methylumbelliferyl)-alpha-D-N-acetylneuraminic acid + H2O
-
 Homo sapiens 4-methyl-umbelliferone + alpha-D-N-acetylneuraminic acid
-
 ?
ganglioside GM3 + H2O
-
 Homo sapiens N-acetylneuraminate + beta-D-galactosyl-(1->4)-beta-D-glucosylceramide
-
 ?
O-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galactonon-2-ulopyranosylonic acid)-(2->3)-O-(beta-D-galactopyranosyl)-(1->4)-O-(beta-D-glucopyranosyl)-octanol + H2O
-
 Homo sapiens ?
-
 ?
O-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galactonon-2-ulopyranosylonic acid)-(2->6)-O-(beta-D-galactopyranosyl)-(1->4)-O-(beta-D-glucopyranosyl)-octanol + H2O
-
 Homo sapiens ?
-
 ?
O-(5-acetamido-9-O-acetyl-3,5-dideoxy-D-glycero-alpha-D-galactonon-2-ulopyranosylonic acid)-(2->3)-O-(beta-D-galactopyranosyl)-(1->4)-O-(beta-D-glucopyranosyl)-octanol + H2O
-
 Homo sapiens ?
-
 ?
O-(5-acetamido-9-O-acetyl-3,5-dideoxy-D-glycero-alpha-D-galactonon-2-ulopyranosylonic acid)-(2->6)-O-(beta-D-galactopyranosyl)-(1->4)-O-(beta-D-glucopyranosyl)-octanol + H2O
-
 Homo sapiens ?
-
 ?
O-(5-glycolylamido-3,5,-dideoxy-D-glycero-alpha-D-galactonon-2-ulopyranosylonic acid)-(2->3)-O-(beta-D-galactopyranosyl)-(1->4)-O-(beta-D-glucopyranosyl)-octanol + H2O
-
 Homo sapiens ?
-
 ?
O-(5-glycolylamido-3,5,-dideoxy-D-glycero-alpha-D-galactonon-2-ulopyranosylonic acid)-(2->6)-O-(beta-D-galactopyranosyl)-(1-> 4)-O-(beta-D-glucopyranosyl)-octanol + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
NEU1 isoform Homo sapiens
NEU2 isoform Homo sapiens
Neu3 isoform Homo sapiens
NEU4 isoform Homo sapiens
neuraminidase
-
 Homo sapiens