Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2,6-anhydro-9-azido-3,5,9-trideoxy-5-(2-hydroxyacetamido)-D-glycero-D-galacto-non-2-enonic acid | - |
Clostridium perfringens | |
2,6-anhydro-9-azido-3,5,9-trideoxy-5-(2-hydroxyacetamido)-D-glycero-D-galacto-non-2-enonic acid | - |
Homo sapiens | |
2,6-anhydro-9-azido-3,5,9-trideoxy-5-(2-hydroxyacetamido)-D-glycero-D-galacto-non-2-enonic acid | - |
Salmonella enterica subsp. enterica serovar Typhimurium | |
2,6-anhydro-9-azido-3,5,9-trideoxy-5-(2-hydroxyacetamido)-D-glycero-D-galacto-non-2-enonic acid | - |
Streptococcus pneumoniae | |
2,6-anhydro-9-azido-3,5,9-trideoxy-5-(2-hydroxyacetamido)-D-glycero-D-galacto-non-2-enonic acid | - |
Vibrio cholerae | |
2,6-anhydro-9-azido-5-(2-azidoacetamido)-3,5,9-trideoxy-D-glycero-D-galacto-non-2-enonic acid | - |
Clostridium perfringens | |
2,6-anhydro-9-azido-5-(2-azidoacetamido)-3,5,9-trideoxy-D-glycero-D-galacto-non-2-enonic acid | - |
Homo sapiens | |
2,6-anhydro-9-azido-5-(2-azidoacetamido)-3,5,9-trideoxy-D-glycero-D-galacto-non-2-enonic acid | - |
Salmonella enterica subsp. enterica serovar Typhimurium | |
2,6-anhydro-9-azido-5-(2-azidoacetamido)-3,5,9-trideoxy-D-glycero-D-galacto-non-2-enonic acid | - |
Streptococcus pneumoniae | |
2,6-anhydro-9-azido-5-(2-azidoacetamido)-3,5,9-trideoxy-D-glycero-D-galacto-non-2-enonic acid | - |
Vibrio cholerae | |
2-deoxy-2,3-dehydro-N-acetylneuraminic acid | - |
Clostridium perfringens | |
2-deoxy-2,3-dehydro-N-acetylneuraminic acid | - |
Homo sapiens | |
2-deoxy-2,3-dehydro-N-acetylneuraminic acid | - |
Salmonella enterica subsp. enterica serovar Typhimurium | |
2-deoxy-2,3-dehydro-N-acetylneuraminic acid | - |
Streptococcus pneumoniae | |
2-deoxy-2,3-dehydro-N-acetylneuraminic acid | - |
Vibrio cholerae | |
5-acetamido-2,6-anhydro-3,5-dideoxy-9-O-methyl-D-glycero-D-galacto-non-2-enonic acid | - |
Clostridium perfringens | |
5-acetamido-2,6-anhydro-3,5-dideoxy-9-O-methyl-D-glycero-D-galacto-non-2-enonic acid | - |
Homo sapiens | |
5-acetamido-2,6-anhydro-3,5-dideoxy-9-O-methyl-D-glycero-D-galacto-non-2-enonic acid | - |
Salmonella enterica subsp. enterica serovar Typhimurium | |
5-acetamido-2,6-anhydro-3,5-dideoxy-9-O-methyl-D-glycero-D-galacto-non-2-enonic acid | - |
Streptococcus pneumoniae | |
5-acetamido-2,6-anhydro-3,5-dideoxy-9-O-methyl-D-glycero-D-galacto-non-2-enonic acid | - |
Vibrio cholerae | |
5-acetamido-2,6-anhydro-9-azido-3,5,9-trideoxy-D-glycero-D-galacto-non-2-enonic acid | - |
Clostridium perfringens | |
5-acetamido-2,6-anhydro-9-azido-3,5,9-trideoxy-D-glycero-D-galacto-non-2-enonic acid | - |
Homo sapiens | |
5-acetamido-2,6-anhydro-9-azido-3,5,9-trideoxy-D-glycero-D-galacto-non-2-enonic acid | - |
Salmonella enterica subsp. enterica serovar Typhimurium | |
5-acetamido-2,6-anhydro-9-azido-3,5,9-trideoxy-D-glycero-D-galacto-non-2-enonic acid | - |
Streptococcus pneumoniae | |
5-acetamido-2,6-anhydro-9-azido-3,5,9-trideoxy-D-glycero-D-galacto-non-2-enonic acid | - |
Vibrio cholerae | |
5-acetamido-9-aminopropyl-2,6-anhydro-3,5,9-trideoxy-D-glycero-D-galacto-non-2-enonic acid | - |
Clostridium perfringens | |
5-acetamido-9-aminopropyl-2,6-anhydro-3,5,9-trideoxy-D-glycero-D-galacto-non-2-enonic acid | - |
Homo sapiens | |
5-acetamido-9-aminopropyl-2,6-anhydro-3,5,9-trideoxy-D-glycero-D-galacto-non-2-enonic acid | - |
Salmonella enterica subsp. enterica serovar Typhimurium | |
5-acetamido-9-aminopropyl-2,6-anhydro-3,5,9-trideoxy-D-glycero-D-galacto-non-2-enonic acid | - |
Streptococcus pneumoniae | |
5-acetamido-9-aminopropyl-2,6-anhydro-3,5,9-trideoxy-D-glycero-D-galacto-non-2-enonic acid | - |
Vibrio cholerae |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Homo sapiens | 5829 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Clostridium perfringens | P10481 | - |
- |
Homo sapiens | Q9Y3R4 | - |
- |
Salmonella enterica subsp. enterica serovar Typhimurium | P29768 | - |
- |
Streptococcus pneumoniae | - |
- |
- |
Vibrio cholerae | P0C6E9 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Neu5Acalpha(2->3)Galbeta-4-nitrophenyl + H2O | - |
Streptococcus pneumoniae | ? | - |
? | |
Neu5Acalpha(2->3)Galbeta-4-nitrophenyl + H2O | - |
Homo sapiens | ? | - |
? | |
Neu5Acalpha(2->3)Galbeta-4-nitrophenyl + H2O | - |
Clostridium perfringens | ? | - |
? | |
Neu5Acalpha(2->3)Galbeta-4-nitrophenyl + H2O | - |
Vibrio cholerae | ? | - |
? | |
Neu5Acalpha(2->3)Galbeta-4-nitrophenyl + H2O | - |
Salmonella enterica subsp. enterica serovar Typhimurium | ? | - |
? | |
Neu5Acalpha(2->6)Galbeta4-nitrophenyl + H2O | - |
Streptococcus pneumoniae | ? | - |
? | |
Neu5Acalpha(2->6)Galbeta4-nitrophenyl + H2O | - |
Homo sapiens | ? | - |
? | |
Neu5Acalpha(2->6)Galbeta4-nitrophenyl + H2O | - |
Clostridium perfringens | ? | - |
? | |
Neu5Acalpha(2->6)Galbeta4-nitrophenyl + H2O | - |
Vibrio cholerae | ? | - |
? | |
Neu5Acalpha(2->6)Galbeta4-nitrophenyl + H2O | - |
Salmonella enterica subsp. enterica serovar Typhimurium | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
NEU2 | - |
Homo sapiens |
neuraminidase | - |
Streptococcus pneumoniae |
neuraminidase | - |
Homo sapiens |
neuraminidase | - |
Clostridium perfringens |
neuraminidase | - |
Vibrio cholerae |
neuraminidase | - |
Salmonella enterica subsp. enterica serovar Typhimurium |
sialidase | - |
Streptococcus pneumoniae |
sialidase | - |
Homo sapiens |
sialidase | - |
Clostridium perfringens |
sialidase | - |
Vibrio cholerae |
sialidase | - |
Salmonella enterica subsp. enterica serovar Typhimurium |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0086 | - |
with Neu5Acalpha(2->3)Galbeta-4-nitrophenyl as substrate, at pH 5.0 and 37°C | Vibrio cholerae | 2-deoxy-2,3-dehydro-N-acetylneuraminic acid | |
0.0087 | - |
with Neu5Acalpha(2->6)Galbeta4-nitrophenyl as substrate, at pH 5.0 and 37°C | Vibrio cholerae | 5-acetamido-2,6-anhydro-9-azido-3,5,9-trideoxy-D-glycero-D-galacto-non-2-enonic acid | |
0.01 | - |
with Neu5Acalpha(2->6)Galbeta4-nitrophenyl as substrate, at pH 5.0 and 37°C | Vibrio cholerae | 2-deoxy-2,3-dehydro-N-acetylneuraminic acid | |
0.013 | - |
with Neu5Acalpha(2->3)Galbeta-4-nitrophenyl as substrate, at pH 5.0 and 37°C | Homo sapiens | 2,6-anhydro-9-azido-5-(2-azidoacetamido)-3,5,9-trideoxy-D-glycero-D-galacto-non-2-enonic acid | |
0.013 | - |
with Neu5Acalpha(2->3)Galbeta-4-nitrophenyl as substrate, at pH 5.0 and 37°C | Vibrio cholerae | 5-acetamido-2,6-anhydro-3,5-dideoxy-9-O-methyl-D-glycero-D-galacto-non-2-enonic acid | |
0.013 | - |
with Neu5Acalpha(2->3)Galbeta-4-nitrophenyl as substrate, at pH 5.0 and 37°C | Salmonella enterica subsp. enterica serovar Typhimurium | 5-acetamido-2,6-anhydro-3,5-dideoxy-9-O-methyl-D-glycero-D-galacto-non-2-enonic acid | |
0.013 | - |
with Neu5Acalpha(2->6)Galbeta4-nitrophenyl as substrate, at pH 5.0 and 37°C | Clostridium perfringens | 2-deoxy-2,3-dehydro-N-acetylneuraminic acid | |
0.013 | - |
with Neu5Acalpha(2->6)Galbeta4-nitrophenyl as substrate, at pH 5.0 and 37°C | Vibrio cholerae | 2,6-anhydro-9-azido-3,5,9-trideoxy-5-(2-hydroxyacetamido)-D-glycero-D-galacto-non-2-enonic acid | |
0.013 | - |
with Neu5Acalpha(2->6)Galbeta4-nitrophenyl as substrate, at pH 5.0 and 37°C | Homo sapiens | 2,6-anhydro-9-azido-5-(2-azidoacetamido)-3,5,9-trideoxy-D-glycero-D-galacto-non-2-enonic acid | |
0.014 | - |
with Neu5Acalpha(2->3)Galbeta-4-nitrophenyl as substrate, at pH 5.0 and 37°C | Vibrio cholerae | 2,6-anhydro-9-azido-5-(2-azidoacetamido)-3,5,9-trideoxy-D-glycero-D-galacto-non-2-enonic acid | |
0.018 | - |
with Neu5Acalpha(2->3)Galbeta-4-nitrophenyl as substrate, at pH 5.0 and 37°C | Homo sapiens | 2-deoxy-2,3-dehydro-N-acetylneuraminic acid | |
0.018 | - |
with Neu5Acalpha(2->3)Galbeta-4-nitrophenyl as substrate, at pH 5.0 and 37°C | Vibrio cholerae | 2,6-anhydro-9-azido-3,5,9-trideoxy-5-(2-hydroxyacetamido)-D-glycero-D-galacto-non-2-enonic acid | |
0.02 | - |
with Neu5Acalpha(2->3)Galbeta-4-nitrophenyl as substrate, at pH 5.0 and 37°C | Clostridium perfringens | 2-deoxy-2,3-dehydro-N-acetylneuraminic acid | |
0.02 | - |
with Neu5Acalpha(2->3)Galbeta-4-nitrophenyl as substrate, at pH 5.0 and 37°C | Salmonella enterica subsp. enterica serovar Typhimurium | 2-deoxy-2,3-dehydro-N-acetylneuraminic acid | |
0.02 | - |
with Neu5Acalpha(2->3)Galbeta-4-nitrophenyl as substrate, at pH 5.0 and 37°C | Vibrio cholerae | 5-acetamido-2,6-anhydro-9-azido-3,5,9-trideoxy-D-glycero-D-galacto-non-2-enonic acid | |
0.021 | - |
with Neu5Acalpha(2->3)Galbeta-4-nitrophenyl as substrate, at pH 5.0 and 37°C | Salmonella enterica subsp. enterica serovar Typhimurium | 5-acetamido-2,6-anhydro-9-azido-3,5,9-trideoxy-D-glycero-D-galacto-non-2-enonic acid | |
0.031 | - |
with Neu5Acalpha(2->6)Galbeta4-nitrophenyl as substrate, at pH 5.0 and 37°C | Homo sapiens | 5-acetamido-2,6-anhydro-9-azido-3,5,9-trideoxy-D-glycero-D-galacto-non-2-enonic acid | |
0.032 | - |
with Neu5Acalpha(2->6)Galbeta4-nitrophenyl as substrate, at pH 5.0 and 37°C | Homo sapiens | 2-deoxy-2,3-dehydro-N-acetylneuraminic acid | |
0.04 | - |
with Neu5Acalpha(2->6)Galbeta4-nitrophenyl as substrate, at pH 5.0 and 37°C | Clostridium perfringens | 5-acetamido-2,6-anhydro-9-azido-3,5,9-trideoxy-D-glycero-D-galacto-non-2-enonic acid | |
0.041 | - |
with Neu5Acalpha(2->6)Galbeta4-nitrophenyl as substrate, at pH 5.0 and 37°C | Homo sapiens | 5-acetamido-2,6-anhydro-3,5-dideoxy-9-O-methyl-D-glycero-D-galacto-non-2-enonic acid | |
0.043 | - |
with Neu5Acalpha(2->3)Galbeta-4-nitrophenyl as substrate, at pH 5.0 and 37°C | Homo sapiens | 5-acetamido-2,6-anhydro-9-azido-3,5,9-trideoxy-D-glycero-D-galacto-non-2-enonic acid | |
0.059 | - |
with Neu5Acalpha(2->3)Galbeta-4-nitrophenyl as substrate, at pH 5.0 and 37°C | Clostridium perfringens | 5-acetamido-2,6-anhydro-9-azido-3,5,9-trideoxy-D-glycero-D-galacto-non-2-enonic acid | |
0.11 | - |
with Neu5Acalpha(2->6)Galbeta4-nitrophenyl as substrate, at pH 5.0 and 37°C | Vibrio cholerae | 2,6-anhydro-9-azido-5-(2-azidoacetamido)-3,5,9-trideoxy-D-glycero-D-galacto-non-2-enonic acid | |
0.12 | - |
with Neu5Acalpha(2->6)Galbeta4-nitrophenyl as substrate, at pH 5.0 and 37°C | Vibrio cholerae | 5-acetamido-2,6-anhydro-3,5-dideoxy-9-O-methyl-D-glycero-D-galacto-non-2-enonic acid | |
0.15 | - |
with Neu5Acalpha(2->3)Galbeta-4-nitrophenyl as substrate, at pH 5.0 and 37°C | Homo sapiens | 2,6-anhydro-9-azido-3,5,9-trideoxy-5-(2-hydroxyacetamido)-D-glycero-D-galacto-non-2-enonic acid | |
0.19 | - |
with Neu5Acalpha(2->6)Galbeta4-nitrophenyl as substrate, at pH 5.0 and 37°C | Homo sapiens | 2,6-anhydro-9-azido-3,5,9-trideoxy-5-(2-hydroxyacetamido)-D-glycero-D-galacto-non-2-enonic acid | |
0.31 | - |
with Neu5Acalpha(2->6)Galbeta4-nitrophenyl as substrate, at pH 5.0 and 37°C | Clostridium perfringens | 5-acetamido-2,6-anhydro-3,5-dideoxy-9-O-methyl-D-glycero-D-galacto-non-2-enonic acid | |
0.46 | - |
with Neu5Acalpha(2->3)Galbeta-4-nitrophenyl as substrate, at pH 5.0 and 37°C | Clostridium perfringens | 5-acetamido-2,6-anhydro-3,5-dideoxy-9-O-methyl-D-glycero-D-galacto-non-2-enonic acid | |
1 | - |
IC50 above 1.0 mM, with Neu5Acalpha(2->3)Galbeta-4-nitrophenyl as substrate, at pH 5.0 and 37°C | Streptococcus pneumoniae | 2,6-anhydro-9-azido-5-(2-azidoacetamido)-3,5,9-trideoxy-D-glycero-D-galacto-non-2-enonic acid | |
1 | - |
IC50 above 1.0 mM, with Neu5Acalpha(2->3)Galbeta-4-nitrophenyl as substrate, at pH 5.0 and 37°C | Clostridium perfringens | 5-acetamido-9-aminopropyl-2,6-anhydro-3,5,9-trideoxy-D-glycero-D-galacto-non-2-enonic acid | |
1 | - |
IC50 above 1.0 mM, with Neu5Acalpha(2->3)Galbeta-4-nitrophenyl as substrate, at pH 5.0 and 37°C | Vibrio cholerae | 5-acetamido-9-aminopropyl-2,6-anhydro-3,5,9-trideoxy-D-glycero-D-galacto-non-2-enonic acid | |
1 | - |
IC50 above 1.0 mM, with Neu5Acalpha(2->6)Galbeta4-nitrophenyl as substrate, at pH 5.0 and 37°C | Clostridium perfringens | 5-acetamido-9-aminopropyl-2,6-anhydro-3,5,9-trideoxy-D-glycero-D-galacto-non-2-enonic acid | |
1 | - |
IC50 above 1.0 mM, with Neu5Acalpha(2->6)Galbeta4-nitrophenyl as substrate, at pH 5.0 and 37°C | Vibrio cholerae | 5-acetamido-9-aminopropyl-2,6-anhydro-3,5,9-trideoxy-D-glycero-D-galacto-non-2-enonic acid | |
1.1 | - |
with Neu5Acalpha(2->3)Galbeta-4-nitrophenyl as substrate, at pH 5.0 and 37°C | Homo sapiens | 5-acetamido-2,6-anhydro-3,5-dideoxy-9-O-methyl-D-glycero-D-galacto-non-2-enonic acid | |
1.2 | - |
with Neu5Acalpha(2->6)Galbeta4-nitrophenyl as substrate, at pH 5.0 and 37°C | Clostridium perfringens | 2,6-anhydro-9-azido-5-(2-azidoacetamido)-3,5,9-trideoxy-D-glycero-D-galacto-non-2-enonic acid | |
1.4 | - |
with Neu5Acalpha(2->6)Galbeta4-nitrophenyl as substrate, at pH 5.0 and 37°C | Clostridium perfringens | 2,6-anhydro-9-azido-3,5,9-trideoxy-5-(2-hydroxyacetamido)-D-glycero-D-galacto-non-2-enonic acid | |
1.6 | - |
with Neu5Acalpha(2->3)Galbeta-4-nitrophenyl as substrate, at pH 5.0 and 37°C | Clostridium perfringens | 2,6-anhydro-9-azido-5-(2-azidoacetamido)-3,5,9-trideoxy-D-glycero-D-galacto-non-2-enonic acid | |
1.9 | - |
with Neu5Acalpha(2->3)Galbeta-4-nitrophenyl as substrate, at pH 5.0 and 37°C | Clostridium perfringens | 2,6-anhydro-9-azido-3,5,9-trideoxy-5-(2-hydroxyacetamido)-D-glycero-D-galacto-non-2-enonic acid | |
2.3 | - |
with Neu5Acalpha(2->3)Galbeta-4-nitrophenyl as substrate, at pH 5.0 and 37°C | Salmonella enterica subsp. enterica serovar Typhimurium | 5-acetamido-9-aminopropyl-2,6-anhydro-3,5,9-trideoxy-D-glycero-D-galacto-non-2-enonic acid | |
2.4 | - |
with Neu5Acalpha(2->6)Galbeta4-nitrophenyl as substrate, at pH 5.0 and 37°C | Homo sapiens | 5-acetamido-9-aminopropyl-2,6-anhydro-3,5,9-trideoxy-D-glycero-D-galacto-non-2-enonic acid | |
3 | - |
with Neu5Acalpha(2->3)Galbeta-4-nitrophenyl as substrate, at pH 5.0 and 37°C | Streptococcus pneumoniae | 5-acetamido-2,6-anhydro-3,5-dideoxy-9-O-methyl-D-glycero-D-galacto-non-2-enonic acid | |
3.3 | - |
with Neu5Acalpha(2->3)Galbeta-4-nitrophenyl as substrate, at pH 5.0 and 37°C | Streptococcus pneumoniae | 5-acetamido-2,6-anhydro-9-azido-3,5,9-trideoxy-D-glycero-D-galacto-non-2-enonic acid | |
3.7 | - |
with Neu5Acalpha(2->3)Galbeta-4-nitrophenyl as substrate, at pH 5.0 and 37°C | Streptococcus pneumoniae | 2-deoxy-2,3-dehydro-N-acetylneuraminic acid | |
5.4 | - |
with Neu5Acalpha(2->3)Galbeta-4-nitrophenyl as substrate, at pH 5.0 and 37°C | Streptococcus pneumoniae | 5-acetamido-9-aminopropyl-2,6-anhydro-3,5,9-trideoxy-D-glycero-D-galacto-non-2-enonic acid | |
10 | - |
IC50 above 10 mM, with Neu5Acalpha(2->3)Galbeta-4-nitrophenyl as substrate, at pH 5.0 and 37°C | Streptococcus pneumoniae | 2,6-anhydro-9-azido-3,5,9-trideoxy-5-(2-hydroxyacetamido)-D-glycero-D-galacto-non-2-enonic acid | |
10 | - |
IC50 above 10 mM, with Neu5Acalpha(2->3)Galbeta-4-nitrophenyl as substrate, at pH 5.0 and 37°C | Salmonella enterica subsp. enterica serovar Typhimurium | 2,6-anhydro-9-azido-3,5,9-trideoxy-5-(2-hydroxyacetamido)-D-glycero-D-galacto-non-2-enonic acid | |
10 | - |
IC50 above 10 mM, with Neu5Acalpha(2->3)Galbeta-4-nitrophenyl as substrate, at pH 5.0 and 37°C | Homo sapiens | 5-acetamido-9-aminopropyl-2,6-anhydro-3,5,9-trideoxy-D-glycero-D-galacto-non-2-enonic acid | |
16 | - |
with Neu5Acalpha(2->3)Galbeta-4-nitrophenyl as substrate, at pH 5.0 and 37°C | Salmonella enterica subsp. enterica serovar Typhimurium | 2,6-anhydro-9-azido-5-(2-azidoacetamido)-3,5,9-trideoxy-D-glycero-D-galacto-non-2-enonic acid |