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Literature summary for 3.2.1.146 extracted from

  • Lo Fiego, M.; Marino, C.; Varela, O.
    Synthesis of galactofuranosyl-(1->5)-thiodisaccharide glycomimetics as inhibitors of a beta-D-galactofuranosidase (2015), RSC Adv., 5, 45631-45640 .
No PubMed abstract available
Search for more literature for 3.2.1.146

Inhibitors

Inhibitors Comment Organism Structure
methyl 5-S-(beta-D-galactofuranosyl)-6-deoxy-5-thio-alpha-L-altrofuranoside competitive inhibitor Penicillium fellutanum
methyl 5-S-(beta-D-galactofuranosyl)-6-deoxy-5-thio-beta-D-galactofuranoside competitive inhibitor Penicillium fellutanum
additional information synthesis of galactofuranosyl-(1->5)-thiodisaccharide glycomimetics as inhibitors of a beta-D-galactofuranosidase, NMR spectrometric structure determination and analysis, overview Penicillium fellutanum

Organism

Organism UniProt Comment Textmining
Penicillium fellutanum
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-nitrophenyl beta-D-galactofuranoside + H2O
-
 Penicillium fellutanum 4-nitrophenol + D-galactofuranose
-
 ?

Synonyms

Synonyms Comment Organism
beta-D-galactofuranosidase
-
 Penicillium fellutanum

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Penicillium fellutanum

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
4.6
-
 assay at Penicillium fellutanum

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.15
-
 methyl 5-S-(beta-D-galactofuranosyl)-6-deoxy-5-thio-beta-D-galactofuranoside pH 4.6, 37°C Penicillium fellutanum
2.23
-
 methyl 5-S-(beta-D-galactofuranosyl)-6-deoxy-5-thio-alpha-L-altrofuranoside pH 4.6, 37°C Penicillium fellutanum