Crystallization (Comment) | Organism |
---|---|
reaction mechanism modelling on crystal structure PDB ID 3SIG | Thermomonospora curvata |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
adenosine diphosphate (hydroxymethyl)-pyrrolidinediol | ADP-HPD | Thermomonospora curvata |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
poly(ADP-D-ribose)n + H2O | Thermomonospora curvata | - |
poly(ADP-D-ribose)n-1 + ADP-ribose | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Thermomonospora curvata | D1AC29 | - |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
(ADP-ribose)n + H2O = (ADP-ribose)n-1 + ADP-ribose | catalytic mechanism, modelling, overview | Thermomonospora curvata |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | hydrolysis of glycosidic ribose-ribose bond | Thermomonospora curvata | ? | - |
? | |
poly(ADP-D-ribose)n + H2O | - |
Thermomonospora curvata | poly(ADP-D-ribose)n-1 + ADP-ribose | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PARG | - |
Thermomonospora curvata |
General Information | Comment | Organism |
---|---|---|
additional information | enzyme structure-function relationship, computational analysis based on the crystal structure, PDB ID 3SIG, modelling of active site structure and SN2 mechanism catalytic mechanism, overview. The oxocarbenium expected by Dea Slade is a possible transition state but not an intermediate. | Thermomonospora curvata |