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Literature summary for 3.2.1.133 extracted from

  • Li, D.; Park, S.H.; Shim, J.H.; Lee, H.S.; Tang, S.Y.; Park, C.S.; Park, K.H.
    In vitro enzymatic modification of puerarin to puerarin glycosides by maltogenic amylase (2004), Carbohydr. Res., 339, 2789-2797.
    View publication on PubMed

Application

Application Comment Organism
medicine pierarin (daidzein 8-C-glucoside), can be used to treat coronary heart disease, cardiac infarction, problems in ocular blood flow, sudden deafness, and alcoholism. However puerarin cannot be given by injection due to its low solubility in water. To increase its solubility, puerarin is transglycosylated using Bacillus stearothermophilus maltogenic amylase. Two major transfer products are alpha-D-glucosyl-(1,6)-puerarin and alpha-D-maltosyl-(1,6)-puerarin. The solubility of the transfer products is 14 and 168 times higher than that of puerarin, respectively Geobacillus stearothermophilus

Organism

Organism UniProt Comment Textmining
Geobacillus stearothermophilus
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Synonyms

Synonyms Comment Organism
BSMA
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Geobacillus stearothermophilus