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Literature summary for 3.2.1.130 extracted from

  • Jensen, K.P.; Stein, M.B.; Kranzler, H.R.; Yang, B.Z.; Farrer, L.A.; Gelernter, J.
    The alpha-endomannosidase gene (MANEA) is associated with panic disorder and social anxiety disorder (2014), Transl. Psychiatry, 4, e353.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
lymphoblastoid cell line
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GlcMan9GlcNAc + H2O
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Homo sapiens Man8GlcNAc + glucosyl alpha1,3-mannose
-
?

Synonyms

Synonyms Comment Organism
alpha-endomannosidase
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Homo sapiens
MANEA
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Homo sapiens

Expression

Organism Comment Expression
Homo sapiens the level of alpha-endomannosidase mRNA is reduced to 89%, 54% and 34% at 2, 5 and 10 h, respectively, after the addition of actinomycin D down

General Information

General Information Comment Organism
physiological function the alpha-endomannosidase gene is associated with panic disorder and social anxiety disorder Homo sapiens